Home / Health Conditions / Hiccups
Hiccups
Hiccups are sudden spasms of the diaphragm followed by a quick closing of the vocal cords. Almost everyone gets them, and they usually stop on their own within minutes. Hiccups that last more than 48 hours, or keep coming back, are worth seeing a doctor about.
See a doctor if hiccups last longer than 48 hours, or keep coming back and are affecting your life (NHS (opens in a new tab)), or if they get in the way of sleeping, eating, drinking or talking (MedlinePlus (opens in a new tab)).
Call 911 for hiccups that come with signs of a heart attack — chest pain or pressure, shortness of breath, pain spreading to the arm, jaw, neck or back, or feeling faint (CDC (opens in a new tab)) — or signs of a stroke: sudden numbness or weakness in the face, arm or leg, sudden confusion or trouble speaking, sudden trouble walking or loss of balance, or a sudden severe headache with no known cause (CDC (opens in a new tab)). Stroke and reduced blood flow to the heart are among the known causes of hiccups (Chang & Lu, 2012 (opens in a new tab)).
See a doctor promptly for vomit that contains blood or looks like coffee grounds, black or tarry stools, trouble swallowing, or weight loss you can’t explain (NIDDK (opens in a new tab)).
What is a hiccup?
A hiccup has two parts. First, the diaphragm — the dome-shaped muscle at the base of the lungs and the main muscle you breathe with — moves suddenly on its own. Then the vocal cords snap shut, which makes the “hic” sound (MedlinePlus (opens in a new tab)). The muscles between the ribs take part in the spasm too (Chang & Lu, 2012 (opens in a new tab)).
Researchers describe a hiccup reflex arc: nerves that carry signals in (the phrenic and vagus nerves and sympathetic nerves), a control center in the brainstem, and nerves that carry the signal back out to the diaphragm and rib muscles (Chang & Lu, 2012 (opens in a new tab), Bowman et al., 2026 (opens in a new tab)). Anything that irritates part of this arc can set off hiccups (Chang & Lu, 2012 (opens in a new tab)).
Common triggers
Hiccups can start and stop for no obvious reason, but they often follow something that irritates the diaphragm (MedlinePlus (opens in a new tab)):
- Big meals and eating fast — eating too much or too quickly, or a bloated stomach (MedlinePlus (opens in a new tab)). Hiccups often come after a large meal or a fizzy drink (GARD (opens in a new tab)). In children, an overfull stomach is the most common cause that can be identified (Leung et al., 2020 (opens in a new tab)).
- Carbonated (fizzy) drinks, alcohol, and hot or spicy food (MedlinePlus (opens in a new tab), NHS (opens in a new tab)).
- Excitement, nerves and stress (MedlinePlus (opens in a new tab), NHS (opens in a new tab)).
- Temperature changes — the NHS advises against eating or drinking something very cold right after something hot (NHS (opens in a new tab)).
- Swallowing air — chewing gum and smoking can make you swallow air (NHS (opens in a new tab)).
Persistent and intractable hiccups
Most hiccups go away by themselves after a few minutes (MedlinePlus (opens in a new tab)). Doctors use two terms for hiccups that don’t (Cochrane review, 2013 (opens in a new tab)):
- Persistent hiccups last more than 48 hours.
- Intractable hiccups last more than one month.
Some authors draw the second line at two months instead (Chang & Lu, 2012 (opens in a new tab)). Either way, long-lasting hiccups are uncommon (Cochrane review, 2013 (opens in a new tab)), but they can cause trouble sleeping, tiredness, weight loss, poor nutrition, and depression or anxiety (GARD (opens in a new tab)). They are much more common in men (Aubignat, 2026 (opens in a new tab)).
What causes hiccups that won’t stop?
In rare cases, hiccups lasting longer than 48 hours are due to a medical condition or a medicine (NHS (opens in a new tab)). More than 100 causes have been reported, and often the exact cause is never found (GARD (opens in a new tab)). The main groups are:
- Digestive problems, the most common group in persistent hiccups along with brain and nerve conditions (Kohse et al., 2017 (opens in a new tab)). Gastroesophageal reflux disease (GERD) is a leading cause (Aubignat, 2026 (opens in a new tab), Chang & Lu, 2012 (opens in a new tab)); see our Acid Reflux & GERD guide. Abdominal surgery can also bring on hiccups (MedlinePlus (opens in a new tab)).
- Irritation of the nerves that control the diaphragm (MedlinePlus (opens in a new tab)) — for example by tumors or a herpes infection along the reflex arc (Chang & Lu, 2012 (opens in a new tab)).
- Central nervous system conditions (MedlinePlus (opens in a new tab)) such as stroke, growths in the brain, or injury (Chang & Lu, 2012 (opens in a new tab)).
- Metabolic disorders (MedlinePlus (opens in a new tab)).
- Heart, lung and infectious conditions, and sometimes psychological causes (Leung et al., 2020 (opens in a new tab)).
- Medicines. Corticosteroids (steroids) and benzodiazepines are the drug groups most often linked to hiccups, though proof that a drug is the cause is usually limited (Thompson & Landry, 1997 (opens in a new tab)). The steroid dexamethasone, often given with chemotherapy to prevent nausea, is a well-studied example (Go et al., 2017 (opens in a new tab)). Never stop a prescribed medicine on your own — ask your doctor.
Finding the cause matters because persistent hiccups can be a sign of a serious illness (Leung et al., 2020 (opens in a new tab)). A doctor will start with your history and an exam; depending on what they find, tests may include blood tests, a chest X-ray, an upper endoscopy or brain imaging (Aubignat, 2026 (opens in a new tab)).
Side by side
Six approaches compared
For every condition we look at the same six approaches: what each involves, what it typically costs, and what a patient can realistically expect.
| Approach | What it involves | Estimated cost | What to expect |
|---|---|---|---|
| Conventional medicine (AMA) | Waiting it out for ordinary hiccups. For persistent hiccups: finding and treating the cause or changing a medicine, an acid-reducing medicine when reflux is suspected, and prescription medicines such as chlorpromazine, baclofen, gabapentin or metoclopramide. Nerve blocks are rarely needed. | Cost estimate being researched. | Ordinary hiccups stop within minutes. Treating the cause should stop hiccups that come from it. Chlorpromazine is the only FDA-approved hiccup medicine and doesn’t work for everyone; the other medicines rest on small studies. |
| Chiropractic | No established role. We found no chiropractic studies of hiccups. | Not applicable. | A few small reports describe osteopathic treatment by physicians, which is a different practice. Hiccups that won’t stop need a medical checkup first. |
| Acupuncture | Fine needles, studied mainly for persistent hiccups in people with cancer or after a stroke, usually alongside medical care. | About $125–$230 for a first private visit and $90–$185 for follow-ups; community clinics about $50–$90. Medicare covers acupuncture only for chronic low back pain. | Case series and small trials are encouraging, but reviewers rate the evidence as too weak to be sure it works. |
| Herbal medicine | Little evidence. Sugar and vinegar are kitchen tricks, not proven treatments. A few Japanese herbal formulas have been tried in hospital patients. | Cost estimate being researched. | Harmless tricks may be worth a try for ordinary hiccups. Herbs can interact with medicines, so ask your doctor or pharmacist first. We don’t list doses. |
| Massage therapy | No role in treating hiccups. | Not applicable. | We found little research. Massage shouldn’t be used to put off seeing a doctor about hiccups that won’t stop. |
| MBHA Wellness Coach | Simple tricks to try, eating more slowly, smaller meals, cutting back on fizzy drinks, alcohol, gum and smoking, avoiding hot-then-cold food and drink, reflux habits, and ways to handle stress. | Cost estimate being researched. | These habits may mean fewer bouts of ordinary hiccups. They support, never replace, a medical checkup for hiccups lasting more than 48 hours. |
Approach 1 of 6
Conventional medicine (AMA)
Most hiccups need no treatment. They usually stop on their own after a few minutes (MedlinePlus (opens in a new tab)), and bouts shorter than 48 hours rarely need a doctor (Leung et al., 2020 (opens in a new tab)).
Treating the cause comes first. A doctor will look for a health condition or a medicine behind persistent hiccups; treating the condition or changing the medicine should stop them (NHS (opens in a new tab)). There are no formal treatment guidelines, and most advice rests on case reports and small studies (Leung et al., 2020 (opens in a new tab)). A 2026 review suggests a step-by-step approach: treat the cause, try an acid-reducing proton pump inhibitor (PPI) first, then baclofen or gabapentin (Aubignat, 2026 (opens in a new tab)). For people whose hiccups come from the steroid dexamethasone given with chemotherapy, switching to a different steroid reduced hiccups in a randomized trial without making nausea worse (Go et al., 2017 (opens in a new tab)).
Medicines for persistent hiccups
We name these medicines so you can talk about them with your doctor. We don’t list doses.
- Chlorpromazine is the only drug approved by the U.S. Food and Drug Administration for hiccups (Kohse et al., 2017 (opens in a new tab)). It is used for hiccups that have lasted a month or longer (MedlinePlus (opens in a new tab)), and the NHS notes it doesn’t work for everyone (NHS (opens in a new tab)). It can cause drowsiness and dizziness or fainting on standing up, and older adults with dementia who take antipsychotics like it have a higher risk of death (MedlinePlus (opens in a new tab)).
- Baclofen, gabapentin and metoclopramide have shown promising results in reports, but large studies are lacking (Kohse et al., 2017 (opens in a new tab)). In a small trial of 30 stroke patients, baclofen stopped hiccups more often than a placebo; some people had mild drowsiness or dizziness (Zhang et al., 2014 (opens in a new tab)). In a pilot trial of 36 people with intractable hiccups, metoclopramide worked better than a placebo, with side effects such as tiredness, low mood and dizziness (Wang & Wang, 2014 (opens in a new tab)).
A Cochrane review found too little good evidence to guide treatment with any medicine or other method; no drug studies met its standards (Cochrane review, 2013 (opens in a new tab)).
Procedures, rarely
When medicines and physical maneuvers fail, doctors may numb the phrenic nerve with a nerve block (Ke et al., 2023 (opens in a new tab), Aubignat, 2026 (opens in a new tab)). Surgery is very rarely used (Leung et al., 2020 (opens in a new tab)).
What it costs
Cost estimate being researched.
Approach 2 of 6
Chiropractic
Chiropractic care has no established role in treating hiccups. A PubMed search we ran in October 2026 for hiccups together with chiropractic, spinal manipulation or spinal adjustment returned no studies.
The nearest research is on osteopathic manipulative treatment (OMT), a hands-on method used by osteopathic physicians, which is a different practice. A pilot study of five people with intractable hiccups found fewer daily hiccups after one session (Bowman et al., 2026 (opens in a new tab)), and a single case report described hiccups from chemotherapy stopping after OMT (Aluri et al., 2026 (opens in a new tab)). Studies this small can’t show that the treatment works.
Spinal manipulation of the neck has been linked to rare tears in neck arteries that can lead to a stroke (NCCIH (opens in a new tab)). Hiccups lasting more than 48 hours need a medical checkup first (NHS (opens in a new tab)).
Approach 3 of 6
Acupuncture
Acupuncture has been studied mostly for persistent hiccups in people with cancer or after a stroke, usually alongside medical care. The evidence is promising but weak.
- A small case series in people with cancer: at the National Institutes of Health, 16 men with cancer and persistent hiccups had one to three acupuncture sessions; hiccups stopped completely in 13 and eased in the other 3 (Ge et al., 2010 (opens in a new tab)). There was no comparison group.
- Cancer-related hiccups, 2024 review: nine randomized trials (580 patients) favored acupuncture over medicines, but every trial had a high risk of bias, and the authors said there is no conclusive evidence yet (Guo et al., 2024 (opens in a new tab)).
- Intractable hiccups, 2025 review: 41 trials, all done in China, suggested benefit, but the authors noted possible bias and uneven quality (Zhai et al., 2025 (opens in a new tab)).
- Cochrane review: the four acupuncture studies that qualified all had a high risk of bias and none compared acupuncture with a placebo (Cochrane review, 2013 (opens in a new tab)).
Safety and cost: relatively few complications have been reported, but nonsterile needles and improper treatment have caused serious harm; most states license acupuncturists (NCCIH (opens in a new tab)). A first private visit is about $125–$230, follow-ups about $90–$185, and community clinics about $50–$90 (The Pricer, 2026 (opens in a new tab)). Medicare covers acupuncture only for chronic low back pain (Medicare.gov (opens in a new tab)).
Approach 4 of 6
Herbal medicine
There is little evidence that any herb treats hiccups.
- Sugar and vinegar: the NHS lists swallowing a little granulated sugar, or biting on a lemon or tasting vinegar, among things people find helpful, while noting there is no evidence they work for everyone (NHS (opens in a new tab)). Home cures like these are unproven but not harmful, so you could try them (MedlinePlus (opens in a new tab)). Vinegar’s research is a single case report in a person with advanced cancer (Gonella & Gonella, 2015 (opens in a new tab)).
- Japanese herbal (Kampo) formulas: shitei (persimmon calyx) extract and a formula called shakuyakukanzoto have been tried in hospital patients in Japan, mostly people with hiccups from chemotherapy or brain disease (Hosoya et al., 2019 (opens in a new tab), Kamoshida et al., 2021 (opens in a new tab)). These were observational studies of hospital records, not randomized trials.
Some herbs interact with prescription medicines (NCCIH (opens in a new tab)), so ask your doctor or pharmacist before trying one, especially if you are being treated for cancer or another serious illness.
Approach 5 of 6
Massage therapy
Massage therapy has no role in treating hiccups, and we found little research on it. It shouldn’t be used to put off seeing a health care provider about a medical problem (NCCIH (opens in a new tab)).
Approach 6 of 6
MBHA Wellness Coach
An MBHA Wellness Coach can help you spot your own triggers and build habits that may mean fewer bouts of hiccups:
- Simple tricks, with honest expectations — holding your breath, sipping ice-cold water, or breathing into a paper bag (never over your head (NHS (opens in a new tab)), and never a plastic bag). See Home tricks: what’s known. In a trial of people having chemotherapy, those taught a set of simple self-help physical and behavioral techniques got rid of acute hiccups faster than those who weren’t (Luo et al., 2025 (opens in a new tab)).
- Eat slowly and don’t overfill. Eating too quickly or too much can irritate the diaphragm (MedlinePlus (opens in a new tab)).
- Cut back on fizzy drinks and alcohol, and on hot drinks and spicy food if they set you off (NHS (opens in a new tab)).
- Skip gum and smoking, which make you swallow air, and avoid something very cold right after something hot (NHS (opens in a new tab)).
- Manage reflux. Since GERD is a common cause of persistent hiccups (Aubignat, 2026 (opens in a new tab)), reflux habits may help — see our Acid Reflux & GERD and Heartburn guides. A hiatus hernia, when part of the stomach moves up into the chest, is one cause of heartburn and acid reflux (NHS (opens in a new tab)); see our Hiatal Hernia guide.
- Handle stress. Stress and strong emotions can trigger hiccups (NHS (opens in a new tab)); our Anxiety guide covers ways to manage it.
Hiccups lasting more than 48 hours still need a doctor (NHS (opens in a new tab)).
Another approach
Home tricks: what’s known
Nearly everyone has a favorite hiccup cure. Here is what the evidence says:
- Things people find helpful include breathing into a paper bag (never over your head), pulling your knees to your chest and leaning forward, sipping ice-cold water, swallowing some granulated sugar, biting on a lemon or tasting vinegar, and holding your breath for a short time (NHS (opens in a new tab)). MedlinePlus adds gargling with ice water (MedlinePlus (opens in a new tab)).
- How well they work: there is no evidence these tricks work for everyone (NHS (opens in a new tab)) and no proof that they work at all, but they are not harmful (MedlinePlus (opens in a new tab)). Most of what is known about hiccup remedies comes from case reports and personal experience (Leung et al., 2020 (opens in a new tab)).
- What reviewers say: a 2012 review lists holding your breath among non-drug measures that have succeeded, while describing folk remedies as convenient but of uncertain effect (Chang & Lu, 2012 (opens in a new tab)).
Hiccups often stop on their own within minutes anyway (MedlinePlus (opens in a new tab)), which is one reason so many cures seem to work.
Another approach
Hiccups that won’t stop
See a doctor if hiccups last longer than 48 hours, or keep coming back and are affecting your life (NHS (opens in a new tab)). Bring:
- how long the hiccups have lasted, and how often they come back;
- a list of every medicine, herb and supplement you take, since some medicines can trigger hiccups (NHS (opens in a new tab), Thompson & Landry, 1997 (opens in a new tab));
- any heartburn, reflux, trouble swallowing or other new symptoms.
Long-lasting hiccups can take a real toll — poor sleep, tiredness, weight loss and low mood (GARD (opens in a new tab)). A good team effort to find the cause matters (Kohse et al., 2017 (opens in a new tab)), and treating that cause or changing a medicine should stop the hiccups (NHS (opens in a new tab)). If you’re having cancer treatment and develop hiccups, tell your care team: switching from or leaving out the steroid dexamethasone has helped in studies, but only your care team should change your medicines (Sutcliffe & Eche-Ugwu, 2026 (opens in a new tab)).
Another approach
Hiccups in babies
Hiccups are common and normal in babies, and babies can even hiccup in the womb, which feels like small, jerky, rhythmic movements (Pregnancy, Birth and Baby (opens in a new tab)).
- A hiccupping baby’s whole body may seem to move, and the hiccups can be loud, but most babies aren’t bothered and are unlikely to feel pain (Pregnancy, Birth and Baby (opens in a new tab)).
- Baby hiccups don’t need treatment and usually stop within a few minutes. You can sit your baby upright and try burping them (Pregnancy, Birth and Baby (opens in a new tab)).
- Hiccups sometimes come with spitting up. If your baby has reflux and seems upset, keeping them upright during and after feeds and offering smaller, more frequent feeds may help (Pregnancy, Birth and Baby (opens in a new tab)).
Call 911 if your baby has trouble breathing, their skin or lips turn blue, or you think they may be choking. Trust your instincts and have your baby checked whenever you feel they need it (Pregnancy, Birth and Baby (opens in a new tab)). In pregnancy, contact your midwife or doctor right away about any change in your baby’s usual movements (Pregnancy, Birth and Baby (opens in a new tab)).
Member stories
Living with Hiccups? Share your experience
Real experiences help others choose. Tell us what you tried — conventional medicine, chiropractic, acupuncture, herbs, massage or coaching — what it cost and what changed.
Sources
- NHS — Hiccups (opens in a new tab)
- MedlinePlus — Hiccups (health topic) (opens in a new tab)
- MedlinePlus — Chlorpromazine (drug information) (opens in a new tab)
- GARD (NIH) — Chronic hiccup (opens in a new tab)
- Pregnancy, Birth and Baby (Healthdirect Australia) — Hiccups (last reviewed October 2025) (opens in a new tab)
- NIDDK — Symptoms & causes of GER & GERD (opens in a new tab)
- NHS — Heartburn and acid reflux (opens in a new tab)
- CDC — About heart attack symptoms, risk, and recovery (opens in a new tab)
- CDC — Signs and symptoms of stroke (opens in a new tab)
- Moretto et al. — Interventions for treating persistent and intractable hiccups in adults (Cochrane review, 2013; PubMed) (opens in a new tab)
- Chang & Lu — Hiccup: mystery, nature and treatment, Journal of Neurogastroenterology and Motility, 2012 (PubMed) (opens in a new tab)
- Kohse et al. — Chronic hiccups: an underestimated problem, Anesthesia & Analgesia, 2017 (PubMed) (opens in a new tab)
- Leung et al. — Hiccups: a non-systematic review, Current Pediatric Reviews, 2020 (PubMed) (opens in a new tab)
- Aubignat — Hiccups in adults: pathophysiology, diagnostic approach, and management, La Revue de Médecine Interne, 2026 (in French; English abstract on PubMed) (opens in a new tab)
- Thompson & Landry — Drug-induced hiccups, Annals of Pharmacotherapy, 1997 (PubMed) (opens in a new tab)
- Go et al. — Antiemetic corticosteroid rotation from dexamethasone to methylprednisolone to prevent dexamethasone-induced hiccup in cancer patients treated with chemotherapy: a randomized, single-blind, crossover phase III trial, The Oncologist, 2017 (PubMed) (opens in a new tab)
- Sutcliffe & Eche-Ugwu — A systematic literature review of interventions to manage hiccups in patients with cancer undergoing active treatment, Cancer Nursing, 2026 (PubMed) (opens in a new tab)
- Zhang et al. — Baclofen for stroke patients with persistent hiccups: a randomized, double-blind, placebo-controlled trial, Trials, 2014 (PubMed) (opens in a new tab)
- Wang & Wang — Metoclopramide for patients with intractable hiccups: a multicentre, randomised, controlled pilot study, Internal Medicine Journal, 2014 (PubMed) (opens in a new tab)
- Ke et al. — Successful termination of persistent hiccups via combined ultrasound and nerve stimulator-guided singular phrenic nerve block: a case report and literature review, Journal of International Medical Research, 2023 (PubMed) (opens in a new tab)
- Ge et al. — Acupuncture treatment for persistent hiccups in patients with cancer, Journal of Alternative and Complementary Medicine, 2010 (PubMed) (opens in a new tab)
- Guo et al. — Effectiveness and safety of acupuncture for cancer-related hiccups: a systematic review and meta-analysis, Frontiers in Neurology, 2024 (PubMed) (opens in a new tab)
- Zhai et al. — Effectiveness and safety of acupuncture therapies for intractable hiccups: a systematic review and network meta-analysis, Frontiers in Medicine, 2025 (PubMed) (opens in a new tab)
- Bowman et al. — Investigating the efficacy of osteopathic manipulative treatment for intractable hiccups: a pilot study, Journal of Osteopathic Medicine, 2026 (PubMed) (opens in a new tab)
- Aluri et al. — Resolution of chemotherapy-induced intractable hiccups following osteopathic manipulative treatment: a case report, Cureus, 2026 (PubMed) (opens in a new tab)
- Hosoya et al. — Investigation into the effect of shitei extract, a traditional Chinese medicine formulation, on hiccups, Gan To Kagaku Ryoho, 2019 (in Japanese; English abstract on PubMed) (opens in a new tab)
- Kamoshida et al. — Effect of shakuyakukanzoto on chemotherapy-induced hiccups in patients with lung cancer, Eurasian Journal of Medicine, 2021 (PubMed) (opens in a new tab)
- Gonella & Gonella — Use of vinegar to relieve persistent hiccups in an advanced cancer patient, Journal of Palliative Medicine, 2015 (PubMed) (opens in a new tab)
- Luo et al. — Patient-directed behavioral-physical interventions to alleviate acute hiccups associated with chemotherapy: a prospective randomized controlled trial, Supportive Care in Cancer, 2025 (PubMed) (opens in a new tab)
- NCCIH — Herb-drug interactions: what the science says (opens in a new tab)
- NCCIH — Spinal manipulation: what you need to know (opens in a new tab)
- NCCIH — Acupuncture: effectiveness and safety (opens in a new tab)
- NCCIH — Massage therapy: what you need to know (opens in a new tab)
- Medicare.gov — Acupuncture (opens in a new tab)
- The Pricer — Acupuncture cost (updated September 2026) (opens in a new tab)
This page is for education only and is not medical advice. Costs are typical U.S. ranges and estimates; yours will depend on your provider, location and insurance. Talk with your doctor before starting, stopping or combining any treatment. In an emergency, call 911. See our disclaimer.
Find the right practitioner
Search MBHA’s Health Directory for doctors, chiropractors, acupuncturists and massage therapists across the Monterey Bay.