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Schizophrenia
Schizophrenia is a serious but treatable mental illness that can change how a person thinks, feels and behaves, including hearing voices or holding beliefs that are not true. Starting care early, staying on prescribed medicine, and adding therapy, family support and help with work or school can make a real difference. This guide also explains how to help a loved one and what to do in a crisis.
If you or someone you know is thinking about suicide, call or text 988 (or chat online) to reach the 988 Suicide & Crisis Lifeline, and in a life-threatening situation call 911 (NIMH (opens in a new tab)). The Lifeline is free, confidential and open 24/7 (988 Lifeline (opens in a new tab)).
Call 911 or go to the nearest emergency room if someone is in danger of hurting themselves or someone else. Examples include voices telling them to do something harmful, threats of violence or self-harm, or being unable to stay safe. People with psychosis may hear voices that give instructions (NHS (opens in a new tab)), and in some cases a person in a psychotic episode may harm themselves or become threatening or violent toward others; the risk of violence and suicide decreases with treatment (NIMH (opens in a new tab)). The risk of suicide is highest in the early stages of illness (NIMH statistics (opens in a new tab)) and may be higher after an acute episode or a hospital stay (NHS (opens in a new tab)).
Get urgent medical help if a person is not eating or drinking. In extreme cases a person with schizophrenia might stop moving or talking for periods of time, a rare condition called catatonia (NIMH (opens in a new tab)). A medical review lists decreased oral intake as a sign of catatonia and malnutrition among its complications (Smith & Holmes, 2023 (opens in a new tab)). Do not wait to see if it passes.
Never stop an antipsychotic medicine suddenly or on your own, even if you feel well. NIMH says not to stop a medication without first talking to a health care provider, who can adjust the plan safely (NIMH (opens in a new tab)). The NHS adds that stopping could bring a relapse of symptoms (NHS (opens in a new tab)). For clozapine, MedlinePlus says your doctor will probably decrease the dose gradually (MedlinePlus (opens in a new tab)).
What is schizophrenia?
Schizophrenia is a serious mental illness that affects how a person thinks, feels and behaves. People with schizophrenia may appear to have lost touch with reality, which can be distressing for them and for family and friends. It can make everyday activities hard, but effective treatments are available, and treatment can help people stay in school, keep a job, become independent and enjoy relationships (NIMH (opens in a new tab)). MedlinePlus is plain that there is no cure, and that medicine can help control many of the symptoms; therapy, family education, rehabilitation and skills training can help with day-to-day life (MedlinePlus (opens in a new tab)). The NHS notes that most people with schizophrenia make a recovery, although many will have occasional relapses (NHS (opens in a new tab)).
People are usually diagnosed between ages 16 and 30, after a first episode of psychosis. Gradual changes in thinking, mood and social functioning often appear before that first episode, and schizophrenia is rare in younger children (NIMH (opens in a new tab)). Across U.S. studies, the prevalence of schizophrenia and related psychotic disorders is estimated at between 0.25% and 0.64% (NIMH statistics (opens in a new tab)).
The three groups of symptoms
- Psychotic symptoms are hallucinations, delusions and thought disorder. Hallucinations are seeing, hearing, smelling, tasting or feeling things that are not there, and hearing voices is common. Delusions are strong beliefs that are not objectively true, such as believing that people on television are sending special messages or that others are trying to hurt you. Thought disorder is unusual or illogical thinking, such as jumping from topic to topic (NIMH (opens in a new tab)). The NHS notes that hallucinations are very real to the person having them, and that the voices are more often rude, critical or abusive than friendly (NHS (opens in a new tab)).
- Negative symptoms are a loss of motivation, less interest in or enjoyment of daily activities, withdrawal from social life, and difficulty showing emotions. They are sometimes mistaken for depression (NIMH (opens in a new tab)), and for laziness or rudeness (NHS (opens in a new tab)).
- Cognitive symptoms are problems with attention, concentration and memory, which can make it hard to follow a conversation or remember appointments. A person’s level of cognitive functioning is one of the best predictors of their day-to-day functioning (NIMH (opens in a new tab)).
Early warning signs
People often show behavior changes before psychosis develops, such as suspiciousness or unease with others, trouble thinking clearly, pulling away from people, a decline in self-care, disrupted sleep, confused speech, or a sudden drop in grades or job performance (NIMH (opens in a new tab)). Because these changes can look like a teenage “phase,” they are easy to miss (NHS (opens in a new tab)). If they intensify or do not go away, reach out to a health care provider (NIMH (opens in a new tab)). In the U.S., first-time psychosis typically goes more than a year before treatment starts, and people tend to do better when effective treatment begins as early as possible (NIMH RAISE (opens in a new tab)).
Common myths
- It is not a “split personality.” Schizophrenia is not dissociative identity disorder (NIMH (opens in a new tab), NHS (opens in a new tab)).
- Most people with schizophrenia are not violent. They are more likely than others to be harmed by other people. The risk of self-harm and violence to others is greatest when the illness is untreated or occurs together with alcohol or drug misuse (NIMH (opens in a new tab)).
What causes it?
The exact cause is unknown, and several factors may contribute. Schizophrenia sometimes runs in families, but many genes appear to be involved and no single gene causes it by itself. Poverty, stressful or dangerous surroundings, and exposure to viruses or nutritional problems before birth may also play a role, and people with schizophrenia are more likely to have subtle differences in some brain areas and connections (NIMH (opens in a new tab)). In identical twins, if one has schizophrenia the other has about a 1 in 2 chance of developing it, compared with about 1 in 100 in the general population, which tells us genes are not the whole story (NHS (opens in a new tab)). Most people with an affected relative will not develop the disorder (MedlinePlus Genetics (opens in a new tab)). Stressful life events can trigger an episode in someone already vulnerable, but they do not cause schizophrenia on their own (NHS (opens in a new tab)). Psychosis is no one’s fault (NHS Likemind (opens in a new tab)).
How it is diagnosed
There is no single test. Diagnosis usually follows an assessment by a mental health professional, such as a psychiatrist, who checks that the symptoms are not caused by another condition (NHS (opens in a new tab)). Psychosis can also come from sleep deprivation, some prescription medicines, and alcohol or drug misuse, and schizophrenia is typically diagnosed by excluding these other causes (NIMH (opens in a new tab)). A psychiatrist may also consider related conditions such as bipolar disorder or schizoaffective disorder, and may assess for depression, anxiety, post-traumatic stress disorder and substance misuse (NHS (opens in a new tab)). See our Bipolar guide, Depression guide and Anxiety guide.
Why steady care matters
NIMH-supported research is working to improve coordinated specialty care, and to identify people likely to develop schizophrenia before psychosis begins, so that treatment can start earlier (NIMH (opens in a new tab)).
Schizophrenia is one of the top 15 leading causes of disability worldwide. Heart disease, liver disease and diabetes contribute to an increased risk of dying younger, partly because these conditions are more common and often go undetected and untreated; an estimated 4.9% of people with schizophrenia die by suicide (NIMH statistics (opens in a new tab)). These facts are a reason to get full care — mental and physical — not a prediction for any one person. Many people recover, and starting treatment as soon as possible after the first episode of psychosis is an important step (NIMH (opens in a new tab)).
Where to start: talk to a primary care provider, who can refer you to a psychologist, psychiatrist or clinical social worker (NIMH (opens in a new tab)). NIMH also lists state and county health departments, insurers, school health centers and employer assistance programs as ways to find a provider (NIMH (opens in a new tab)). For early psychosis, NIMH points to the Early Psychosis Intervention Network clinics in 17 states and to SAMHSA’s Early Serious Mental Illness Treatment Locator (NIMH (opens in a new tab)).
Side by side
Six approaches compared
For every condition we look at the same six approaches: what each involves, what it typically costs, and what a patient can realistically expect.
| Approach | What it involves | Estimated cost | What to expect |
|---|---|---|---|
| Conventional medicine (AMA) | Care from a psychiatric team: antipsychotic medicine (as daily pills or liquid, or as a long-acting injection given every few weeks), therapy such as CBT for psychosis and family education, help with work or school, and for a first episode, coordinated specialty care. Clozapine for symptoms that don’t improve with usual medicines. Hospital or crisis care when needed. | Outpatient care under Medicare Part B is 20% of the approved amount after the deductible; inpatient psychiatric care under Part A has a 2026 deductible of $1,736. All Marketplace plans must cover mental health care, and Medicaid is the largest payer for mental health services. 988 is free. Medicine prices being researched. | There is no cure, but medicine and therapy can control symptoms for many people, and many people recover, with occasional relapses. Starting early and staying in treatment gives the best chance. |
| Chiropractic | No role in treating schizophrenia. Chiropractic care is for spine and joint problems and does not treat psychosis. | About $55–$100 for a follow-up visit and $90–$200 for a first visit, if you choose it for a back or neck problem. | We found little research on chiropractic care for schizophrenia. It should never replace medicine or therapy. |
| Acupuncture | Needle sessions added to — never in place of — medicine and therapy. | About $125–$230 for a first private visit and $90–$185 for follow-ups; community clinics about $50–$90. | Many studies, of limited quality. In the only sham-controlled comparison (two small studies) a 2026 review found no clear advantage, so the evidence is uncertain. |
| Herbal medicine | Omega-3 fatty acids, ginkgo and Chinese herbal formulas have been tested as add-ons to antipsychotics. None is a proven treatment. St. John’s wort should be avoided. | Cost estimate being researched. | Small or limited trials, some tentatively encouraging, none a replacement for medicine. Supplements can interact with medicines, and St. John’s wort has case reports of worsening psychotic symptoms. |
| Massage therapy | Relaxing hands-on bodywork for stress, alongside standard care. | At one national chain, about $125–$160 for a 60-minute massage for non-members, and memberships about $70–$90 a month; prices vary by location. | May help you relax, but we found little research in schizophrenia and it does not treat psychosis. Low risk with a trained therapist. |
| MBHA Wellness Coach | A steady sleep and daily routine, a medicine routine, spotting early warning signs, a written crisis plan, physical activity and healthy eating, help quitting smoking, avoiding alcohol and drugs, and connecting you and your family with support. | Cost estimate being researched. | Healthy routines and early action support treatment and may help prevent relapse, but they don’t replace medicine, therapy or a psychiatric team. |
Approach 1 of 6
Conventional medicine (AMA)
Treatment focuses on managing symptoms, improving day-to-day functioning and reaching personal goals such as finishing school, working and having good relationships (NIMH (opens in a new tab)). The NHS describes schizophrenia as usually treated with an individually tailored combination of medicine and talking therapy (NHS (opens in a new tab)). We name medicine categories only — your prescriber chooses the medicine and the dose.
1. Antipsychotic medicine
- What it does. Antipsychotic medicine can make psychotic symptoms less intense and less frequent. It is usually taken every day as a pill or liquid, and some forms are given by injection once or twice a month (NIMH (opens in a new tab)). Agitation and hallucinations typically go away within days, delusions usually within a few weeks, and the full effect can take up to 6 weeks (NIMH (opens in a new tab)).
- Two main types. Older, first-generation (“typical”) medicines and newer, second-generation (“atypical”) medicines (NHS (opens in a new tab)). The choice should follow a discussion between you and your psychiatrist about likely benefits and side effects (NHS (opens in a new tab)). Some people need to try several before finding the one that works best (NIMH (opens in a new tab)).
- Long-acting injectables. The NHS describes slow-release (“depot”) antipsychotics given as an injection every 1 to 4 weeks (NHS (opens in a new tab)). In a 2021 review of 137 studies, long-acting injectables were linked to a lower risk of hospitalization or relapse than oral antipsychotics in each type of study. In the randomized trials the difference was modest, so injectables are an option to discuss, not a rule (Kishimoto et al., 2021 (opens in a new tab)). NIMH suggests talking with your provider about side effects, cost and whether you prefer a daily pill or a monthly injection (NIMH (opens in a new tab)).
- Clozapine. If symptoms do not improve with usual antipsychotic medicine, a provider may prescribe clozapine; people taking it must have regular blood tests to check for a potentially dangerous side effect that occurs in 1% to 2% of patients (NIMH (opens in a new tab)). MedlinePlus warns of a severe drop in white blood cells, seizures and heart inflammation, and says to call your doctor right away for signs of infection such as fever or a sore throat. Talk to your doctor if you do not take clozapine for 2 days or longer (MedlinePlus (opens in a new tab)).
Side effects and safety
- Common side effects when starting include weight gain, dry mouth, restlessness and drowsiness. Some go away over time and others last, so report them to your provider (NIMH (opens in a new tab)). The NHS adds blurred vision, constipation, reduced sex drive and, with older medicines, shaking and muscle spasms. Cholesterol, blood sugar and blood pressure may need monitoring (NHS (opens in a new tab)).
- Long-term use of older (typical) medicines may lead to tardive dyskinesia, uncontrollable muscle movements that range from mild to severe. If you think you have it, check with your provider before stopping the medicine. Providers may ask people taking newer medicines to have weight, glucose and lipids monitored regularly (NIMH (opens in a new tab)).
- The FDA requires all antipsychotics to carry a black box warning about increased rates of stroke and death in older adults with dementia (NIMH (opens in a new tab)).
- If you take antipsychotic medicine and stop smoking, or start again, talk to your doctor or psychiatrist, because your prescription may need to be monitored and adjusted (NHS (opens in a new tab)).
Stay on your medicine and talk before changing anything. Take it as prescribed even if you start to feel better, since continuous medicine helps prevent relapse (NHS (opens in a new tab)). Stopping a medicine too soon may cause unpleasant or harmful effects (NIMH (opens in a new tab)). Most people take medicine for 1 or 2 years after a first episode to prevent further episodes, and for longer if the illness is recurrent (NHS (opens in a new tab)). If side effects are hard to live with, ask about alternatives rather than stopping (NHS (opens in a new tab)).
2. Therapy and skills programs
Psychosocial treatments help people find solutions to everyday challenges while attending school, working and forming relationships. People who take part regularly are less likely to relapse or be hospitalized. Examples are cognitive behavioral therapy (CBT), behavioral skills training, supported employment and cognitive remediation (NIMH (opens in a new tab)).
- CBT. In CBT you can learn to recognize examples of delusional thinking and get help avoiding acting on those thoughts. It usually takes a series of hour-long sessions over several months (NHS (opens in a new tab)).
- Family education and therapy. Programs teach family and friends about symptoms and treatment, help them manage their own distress and build coping skills (NIMH (opens in a new tab)). A network analysis of 72 studies with 10,364 people found that family interventions, relapse prevention programs, CBT, family psychoeducation and patient psychoeducation each reduced relapse at one year compared with usual care, although confidence in the estimates ranged from moderate to very low (Bighelli et al., 2021 (opens in a new tab)). A second analysis of 90 trials found almost all family intervention models cut relapse, and that family psychoeducation alone was superior to the more complex models (Rodolico et al., 2022 (opens in a new tab)).
- Supported employment. A meta-analysis of 17 trials found that individual placement and support was more than twice as likely to lead to competitive employment as traditional vocational rehabilitation (Modini et al., 2016 (opens in a new tab)).
- Arts therapies have been shown to ease negative symptoms for some people (NHS (opens in a new tab)).
3. When more support is needed
- Assertive community treatment is a team approach for people likely to have repeated hospitalizations or homelessness (NIMH (opens in a new tab)).
- Hospital care. A very severe episode may require inpatient care (NHS (opens in a new tab)).
- Advance planning. A written crisis plan or advance statement can say what you want family or friends to do and whom to contact if you become unwell again. It is not legally binding, but care teams follow it whenever possible (NHS (opens in a new tab)). See the early psychosis and family sections below.
What it costs
- Medicare Part B (outpatient): covers psychiatric evaluation, medication management, individual, group and family counseling, partial hospitalization and intensive outpatient programs, plus certain injections that are not usually self-administered. After the deductible you pay 20% of the Medicare-approved amount, and hospital outpatient departments may add a copayment (Medicare.gov (opens in a new tab)).
- Medicare Part A (inpatient): in 2026 each benefit period has a $1,736 deductible, then $0 a day for days 1–60, $434 a day for days 61–90 and $868 a day for lifetime reserve days. Part A pays for up to 190 days of care in a psychiatric hospital over your lifetime (Medicare.gov (opens in a new tab)).
- Marketplace plans cover psychotherapy, counseling, inpatient mental health services and substance use treatment as essential health benefits, and cannot charge more for a pre-existing condition (HealthCare.gov (opens in a new tab)). Medicaid is the single largest payer for mental health services in the U.S. (Medicaid.gov (opens in a new tab)).
- Therapy without insurance: the nonprofit Open Path Collective offers individual sessions at $40–$70 and family sessions at $40–$80 after a one-time $65 membership fee (Open Path Collective (opens in a new tab)). Open Path is therapy only, and serious illness usually needs a psychiatric prescriber too.
- Prescription medicines, injections and lab tests: MBHA cost estimate being researched. The 988 Lifeline is free (988 Lifeline (opens in a new tab)).
How well it works — what to expect
Schizophrenia has no cure, but medicine can control many of the symptoms (MedlinePlus (opens in a new tab)). The NHS says most people make a recovery, with occasional relapses (NHS (opens in a new tab)), and that recognizing the signs of an acute episode, taking medicine as prescribed and talking to others can reduce the chance of severe relapses (NHS (opens in a new tab)). Treatment aims to help people stay in school, keep working and enjoy relationships, which is why therapy, rehabilitation and support matter as much as medicine (NIMH (opens in a new tab)).
Approach 2 of 6
Chiropractic
Chiropractic care has no role in treating schizophrenia. It focuses on the spine and joints and cannot treat psychosis. We found little research on chiropractic care as a treatment for schizophrenia, and what treats schizophrenia is the care described in the conventional section (NIMH (opens in a new tab)). Never use it in place of medicine, therapy or a psychiatric team.
If you choose it for a separate problem
Many people with schizophrenia also have everyday aches such as back or neck pain. Mild side effects are common after spinal manipulation, such as soreness, stiffness or headache, and most go away within 24 hours. Serious problems are very rare. Tell any practitioner about your health conditions and medicines, because a serious problem may be more likely in people with underlying health problems (NCCIH (opens in a new tab)).
What it costs
A first appointment commonly runs about $90–$200, and a self-pay follow-up about $55–$100. Multi-visit plans can add up to $500–$1,000 (The Pricer (opens in a new tab)).
Approach 3 of 6
Acupuncture
Acupuncture is sometimes explored as an add-on for schizophrenia, particularly in China. The research is limited in quality, and it should only ever be added to — never used in place of — medicine and therapy.
What the research says
- A Cochrane review of 30 trials found that all were at moderate risk of bias. It concluded that limited evidence suggests acupuncture added to standard antipsychotics may help global and mental state, with few side effects, and that better designed large studies are needed (Shen et al., 2014 (opens in a new tab)).
- A 2026 review pooled 55 trials with 4,256 people. Acupuncture plus antipsychotics improved overall symptoms compared with antipsychotics alone (low certainty), but not compared with sham acupuncture, and only two small studies made that comparison. The authors say this leaves the specific effect of acupuncture uncertain (Choi et al., 2026 (opens in a new tab)).
In short: acupuncture may feel calming for some people, but it is not proven to treat schizophrenia. If you try it, keep taking your medicine and tell your psychiatric provider.
Safety
Relatively few complications have been reported. Problems have come from non-sterile needles and poor technique; the FDA requires acupuncture needles to be sterile and single-use, and most states license acupuncturists (NCCIH (opens in a new tab)). Choose a licensed practitioner.
What it costs
Private sessions run about $125–$230 for a first visit and $90–$185 for follow-ups; community clinics with shared rooms charge about $50–$90 (The Pricer (opens in a new tab)).
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Herbal medicine
No herb or supplement replaces antipsychotic medicine. Dietary supplements are not approved by the FDA before they are sold (NCCIH (opens in a new tab)), and the FDA can’t test all of them; products have been found to contain hidden prescription drugs, and “natural” does not always mean safe (NCCIH (opens in a new tab)). The NHS advises checking with your healthcare team before taking any over-the-counter remedy or nutritional supplement, since these can interfere with your medicine (NHS (opens in a new tab)).
St. John’s wort — avoid it
NCCIH notes case reports of St. John’s wort worsening psychotic symptoms in people with bipolar disorder or schizophrenia (NCCIH (opens in a new tab)). It also interacts, in sometimes life-threatening ways, with many medicines (NCCIH (opens in a new tab)). Don’t take it without your prescriber’s advice.
What has been studied
These are research findings, not treatment recommendations. We found no supplement that has been shown to treat schizophrenia.
- Omega-3 fatty acids (fish oil). A 2021 meta-analysis of 20 double-blind trials with 1,494 people found that adding omega-3s to treatment was associated with improved symptoms, mainly general and positive symptoms but not negative ones. The authors called the findings tentative and said larger studies are needed (Goh et al., 2021 (opens in a new tab)).
- Ginkgo extract. A 2015 review of 8 placebo-controlled trials with 1,033 people reported benefit on total and negative symptoms when it was added to antipsychotics. All the trials were done in China, and the authors said its safety needs more evidence (Chen et al., 2015 (opens in a new tab)).
- Chinese herbal medicine. A 2005 Cochrane review of seven trials found that herbal medicine combined with antipsychotics may be beneficial, but in the one trial comparing herbs against antipsychotics, people did better on the antipsychotic. The authors said traditional Chinese medicine is under-evaluated (Rathbone et al., 2005 (opens in a new tab)).
Before you try any herb or supplement, talk with your prescriber or pharmacist, especially if you take clozapine or another antipsychotic. Never use a supplement in place of prescribed medicine. We don’t list doses here.
Approach 5 of 6
Massage therapy
Massage can be a pleasant way to relax and ease muscle tension. We found little research on massage for schizophrenia, and it does not treat psychosis. The best-known study is very small: six hospitalized people with residual schizophrenia received a foot bath and leg massage three times a week for four weeks, and symptom scores and quality of life scores improved. With only six people measured before and after, it can’t show that massage caused the change (Kito & Suzuki, 2016 (opens in a new tab)).
Safety
The risk of harm appears to be low. Rare serious problems such as a blood clot, nerve injury or broken bone have occurred, sometimes with vigorous deep-tissue massage or in frail older adults. Forty-five states and the District of Columbia license or certify massage therapists (NCCIH (opens in a new tab)). Tell the therapist about your health conditions and medicines, go at your own pace and speak up if you want to stop.
What it costs
Prices vary by location. At one national chain, published franchise price lists show about $125–$160 for a 60-minute massage for non-members and about $65–$90 for additional member sessions, and memberships run about $70–$90 a month (The Pricer (opens in a new tab)). Tips are extra.
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MBHA Wellness Coach
An MBHA Wellness Coach can help you build the everyday habits that support your treatment. These habits work best alongside medicine, therapy and your psychiatric team; they don’t replace them. A coach is not a clinician and doesn’t diagnose or change treatment.
Medicine routines and a care plan
The NHS advises taking medicine as prescribed even when you feel better (NHS (opens in a new tab)). A coach can help you set up reminders and keep a list of questions and side effects to bring to appointments, and help you write down your care plan.
Know your early warning signs
Learning to recognize the signs that you are becoming unwell can help you manage the illness. Signs can include losing your appetite, feeling anxious or stressed, disturbed sleep, feeling suspicious or fearful, worrying about other people’s motives, hearing quiet voices now and again, and finding it hard to concentrate. You may want to ask someone you trust to tell you if they notice your behavior changing (NHS (opens in a new tab)). Catching a relapse early may mean it can be prevented with medicine and extra support (NHS (opens in a new tab)). A coach can help you write your own list and share it with your care team.
Sleep, stress and routine
The NHS advises a regular sleep pattern, avoiding too much stress, and giving the week some structure, even if you are not working (NHS (opens in a new tab)). Disrupted sleep is also one of the warning signs of psychosis (NIMH (opens in a new tab)), so notice and report changes.
Move your body
A 2024 network meta-analysis of 47 studies with 4,031 people found that several kinds of exercise, including yoga and combined resistance and aerobic exercise, were linked to better symptoms, quality of life, mood or thinking in schizophrenia (Yang et al., 2024 (opens in a new tab)). A coach can help you choose something you enjoy and build up gradually. Check with your doctor first, especially if you have heart or metabolic problems.
Eating well and quitting smoking
A balanced diet with plenty of fruit and vegetables and regular exercise can reduce your risk of cardiovascular disease and diabetes. Stopping smoking has been shown to improve the mental health of people with schizophrenia (NHS (opens in a new tab)). See the physical health section below.
Avoid alcohol and drugs
Regularly drinking too much alcohol or using illegal drugs can trigger psychosis and make symptoms of schizophrenia worse, and drugs and alcohol can react badly with antipsychotic medicines. If you find it hard to stop, ask your care team for help (NHS (opens in a new tab)). See the section below.
Build connection and purpose
Peer support from a trained worker who has recovered from psychosis or schizophrenia, day centers, work projects and supported housing are all options the NHS describes (NHS (opens in a new tab)). NIMH suggests looking for support groups and family education programs, such as those offered by the National Alliance on Mental Illness (NIMH (opens in a new tab)). A coach can help you explore what is available locally and set small goals around school, work or volunteering. If things feel unbearable, call or text 988 (988 Lifeline (opens in a new tab)).
What it costs
Cost estimate being researched.
Another approach
Early psychosis and coordinated specialty care
When someone has a first episode of psychosis, the earliest care matters most. Coordinated specialty care (CSC) is a recovery-focused team program for first-episode psychosis. Professionals work together to provide psychotherapy, medication, case management, employment and education services, and family education and support, and the team makes treatment decisions together with the person and their family (NIMH (opens in a new tab)).
- The parts of CSC. Individual or group therapy tailored to your recovery goals; family support and education; medication management; supported employment and education with a coach; and case management for practical problems (NIMH RAISE (opens in a new tab)).
- The evidence. In NIMH’s RAISE research, people who received CSC stayed in treatment longer and improved more in symptoms, relationships and quality of life than those who received typical care, and they were more involved in work and school (NIMH RAISE (opens in a new tab)). A 2018 meta-analysis of 10 randomized trials with 2,176 people found early intervention services better than usual treatment on all 13 outcomes it could analyze, including fewer hospitalizations and less treatment dropout (Correll et al., 2018 (opens in a new tab)). NIMH says CSC is now the standard of care for early psychosis (NIMH (opens in a new tab)).
- Hope. With early diagnosis and appropriate treatment it is possible to recover from psychosis. Some people who receive early treatment never have another episode; for others, recovery means living a fulfilling life even if symptoms sometimes return (NIMH (opens in a new tab)).
- Finding a program. NIMH lists the Early Psychosis Intervention Network clinics, the Psychosis-Risk and Early Psychosis Program Network directory, SAMHSA’s Early Serious Mental Illness Treatment Locator and the NAMI HelpLine (NIMH (opens in a new tab)). If you are a young person or the parent of one, ask a primary care provider about early psychosis programs.
Another approach
For families: how to respond and how to help
It can be hard to know what to do when someone you love is experiencing psychosis. Here is what health agencies suggest.
When they are hearing voices or holding unusual beliefs
- Remember that their beliefs or hallucinations seem very real to them (NIMH (opens in a new tab)). A delusion is held with complete conviction (NHS (opens in a new tab)).
- Listen and try to understand what they are telling you and why they think the way they do. People with psychosis have said the worst thing is being told they are wrong, and doing so can leave them more defensive, angry or upset (NHS Likemind (opens in a new tab)).
- Be respectful, supportive and kind without tolerating dangerous or inappropriate behavior (NIMH (opens in a new tab)).
- Don’t blame them or tell them to “pull themselves together,” and don’t be critical or angry. Psychosis is no one’s fault, and negative comments undermine their efforts (NHS (opens in a new tab), NHS Likemind (opens in a new tab)).
- Don’t force or pressure them to do things they aren’t ready for, and let them recover at their own pace while still encouraging small steps (NHS Likemind (opens in a new tab)).
- Support independence rather than trying to protect them from every stress (NHS Likemind (opens in a new tab)).
Helping them get and stay in treatment
- A person may not think they need help, and it can be hard to persuade them to see a doctor (NHS (opens in a new tab)). Help them get treatment and encourage them to stay in it (NIMH (opens in a new tab)).
- Friends and family can play a major role by noticing the person’s mental state, watching for signs of relapse, and encouraging medicine and appointments (NHS (opens in a new tab)).
- Ask whether you can give input to the care plan. Your observations can help the team, and knowing the plan helps you support it (NHS Likemind (opens in a new tab)).
- Have a crisis plan, agreed when the person is well, that sets out what helps and who to contact (NHS Likemind (opens in a new tab), NHS (opens in a new tab)).
Warning signs of suicide
The NHS lists making final arrangements such as giving away possessions or saying goodbye, talking about death, self-harm, and a sudden lifting of mood. If you see these signs, get professional help, tell the person they are not alone, and stay with them if there is immediate danger. Remove available means such as sharp objects and medication (NHS (opens in a new tab)). In the U.S., call or text 988, or call 911 in a life-threatening situation (NIMH (opens in a new tab)).
Looking after yourself
Having a relative with psychosis can be upsetting and stressful for you too. Keep calm, make time for yourself and get the support you need (NHS Likemind (opens in a new tab)). Family education programs can help families manage their own distress, build coping skills and strengthen their ability to provide support (NIMH (opens in a new tab)). Ask the care team about family psychoeducation or family therapy; the NHS describes sessions over about six months that cover information about the illness, practical problem-solving and planning for a crisis (NHS (opens in a new tab)).
Another approach
Physical health and living well
Physical health deserves as much attention as mental health. Heart disease, liver disease and diabetes contribute to the higher risk of dying younger among people with schizophrenia, and possible reasons include higher rates of these conditions and under-detection and under-treatment of them. NIMH puts the estimated average potential life lost in the U.S. at 28.5 years (NIMH statistics (opens in a new tab)). That is a population average and a reason to act, not a forecast for you.
- Regular check-ups. The NHS advises a check-up at least once a year to monitor the risk of cardiovascular disease and diabetes, including weight, blood pressure and blood tests, and says the care plan should include a healthy eating and physical activity programme and support to give up smoking (NHS (opens in a new tab), NHS (opens in a new tab)).
- Medicine monitoring. Weight, glucose and lipid levels may be checked regularly for people taking newer antipsychotics (NIMH (opens in a new tab)).
- Speak up about physical symptoms. One reason for early death is that medical conditions go under-detected and under-treated (NIMH statistics (opens in a new tab)), so mention new symptoms and ask for checks.
- Other mental health conditions. About half of people with schizophrenia have a co-occurring mental or behavioral health disorder (NIMH statistics (opens in a new tab)). See our Depression and Anxiety guides.
Another approach
Cannabis, alcohol and other drugs
Many people with schizophrenia also have problems with drugs and alcohol. Substance use can interfere with schizophrenia treatment, so NIMH says a program that treats both is important for recovery (NIMH (opens in a new tab)). Substance misuse is more common in people with schizophrenia than in the general population (MedlinePlus Genetics (opens in a new tab)).
- Cannabis and risk. Studies have shown that using drugs, particularly cannabis, cocaine, LSD or amphetamines, can increase the risk of developing schizophrenia or psychosis, and teenagers and young adults who use cannabis regularly are more likely to develop schizophrenia later; the risk may be higher with stronger forms. It is not clear whether drugs directly cause the symptoms or whether people at risk are more likely to use them (NHS (opens in a new tab)). MedlinePlus Genetics says some studies show young people who use cannabis frequently may have an increased risk (MedlinePlus Genetics (opens in a new tab)). A meta-analysis of 10 studies with 66,816 people found that heavier cannabis use was linked to a higher risk of psychosis, with a dose-response pattern, though a causal link cannot be unequivocally established (Marconi et al., 2016 (opens in a new tab)).
- After an episode. If someone has had psychosis before, using drugs can cause a relapse or stop symptoms from getting better. Alcohol and drugs can also cause depression and anxiety and can react badly with antipsychotic medicines (NHS (opens in a new tab), NHS (opens in a new tab)).
- Overdose risk. If drug use is part of the picture, learn the signs of an overdose; see our Drug Overdose guide.
- Asking for help. Tell your care coordinator or doctor if you find it hard to stop (NHS (opens in a new tab)). Combined treatment for schizophrenia and substance use is what NIMH recommends (NIMH (opens in a new tab)).
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Real experiences help others choose. Tell us what you tried — conventional medicine, chiropractic, acupuncture, herbs, massage or coaching — what it cost and what changed.
Sources
- 988 Suicide & Crisis Lifeline (opens in a new tab)
- National Institute of Mental Health (NIMH) — Schizophrenia (publication, revised 2024) (opens in a new tab)
- NIMH — Schizophrenia (health topic) (opens in a new tab)
- NIMH — Schizophrenia (statistics) (opens in a new tab)
- NIMH — Understanding psychosis (opens in a new tab)
- NIMH — Recovery After an Initial Schizophrenia Episode (RAISE) (opens in a new tab)
- NIMH — Mental health medications (opens in a new tab)
- NIMH — Help for mental illnesses (opens in a new tab)
- NHS — Schizophrenia: overview (opens in a new tab)
- NHS — Schizophrenia: symptoms (opens in a new tab)
- NHS — Schizophrenia: causes (opens in a new tab)
- NHS — Schizophrenia: diagnosis (opens in a new tab)
- NHS — Schizophrenia: treatment (opens in a new tab)
- NHS — Schizophrenia: living with (opens in a new tab)
- NHS Likemind — How to help your friend or relative (psychosis) (opens in a new tab)
- MedlinePlus — Schizophrenia (health topic) (opens in a new tab)
- MedlinePlus Genetics — Schizophrenia (opens in a new tab)
- MedlinePlus — Clozapine (opens in a new tab)
- Smith & Holmes — Catatonia: a narrative review for hospitalists, American Journal of Medicine Open, 2023 (opens in a new tab)
- Bighelli et al. — Psychosocial and psychological interventions for relapse prevention in schizophrenia: a systematic review and network meta-analysis, Lancet Psychiatry, 2021 (opens in a new tab)
- Rodolico et al. — Family interventions for relapse prevention in schizophrenia: a systematic review and network meta-analysis, Lancet Psychiatry, 2022 (opens in a new tab)
- Kishimoto et al. — Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis, Lancet Psychiatry, 2021 (opens in a new tab)
- Modini et al. — Supported employment for people with severe mental illness: systematic review and meta-analysis of the international evidence, British Journal of Psychiatry, 2016 (opens in a new tab)
- Correll et al. — Comparison of early intervention services vs treatment as usual for early-phase psychosis: a systematic review, meta-analysis, and meta-regression, JAMA Psychiatry, 2018 (opens in a new tab)
- Marconi et al. — Meta-analysis of the association between the level of cannabis use and risk of psychosis, Schizophrenia Bulletin, 2016 (opens in a new tab)
- Yang et al. — Optimal exercise dose and type for improving schizophrenia symptoms in adults: a systematic review and Bayesian network meta-analysis, Neuroscience & Biobehavioral Reviews, 2024 (opens in a new tab)
- Shen et al. — Acupuncture for schizophrenia, Cochrane Database of Systematic Reviews, 2014 (opens in a new tab)
- Choi et al. — Acupuncture as adjunctive treatment for schizophrenia: a systematic review and meta-analysis, Asian Journal of Psychiatry, 2026 (opens in a new tab)
- Goh et al. — Effects of omega-3 polyunsaturated fatty acid supplements on psychopathology and metabolic parameters in schizophrenia: a meta-analysis of randomized controlled trials, Journal of Psychopharmacology, 2021 (opens in a new tab)
- Rathbone et al. — Chinese herbal medicine for schizophrenia, Cochrane Database of Systematic Reviews, 2005 (opens in a new tab)
- Chen et al. — Efficacy and safety of extract of Ginkgo biloba as an adjunct therapy in chronic schizophrenia: a systematic review of randomized, double-blind, placebo-controlled studies with meta-analysis, Psychiatry Research, 2015 (opens in a new tab)
- Kito & Suzuki — Research on the effect of the foot bath and foot massage on residual schizophrenia patients, Archives of Psychiatric Nursing, 2016 (opens in a new tab)
- NCCIH — St. John's wort and depression: in depth (opens in a new tab)
- NCCIH — St. John's wort (opens in a new tab)
- NCCIH — Using dietary supplements wisely (opens in a new tab)
- NCCIH — Acupuncture: effectiveness and safety (opens in a new tab)
- NCCIH — Massage therapy: what you need to know (opens in a new tab)
- NCCIH — Spinal manipulation: what you need to know (opens in a new tab)
- Medicare.gov — Mental health care (outpatient) (opens in a new tab)
- Medicare.gov — Mental health care (inpatient) (opens in a new tab)
- HealthCare.gov — Mental health & substance abuse coverage (opens in a new tab)
- Medicaid.gov — Behavioral health services (opens in a new tab)
- Open Path Collective — Affordable therapy (nonprofit; its own published prices) (opens in a new tab)
- The Pricer — Chiropractor and chiropractic treatment cost (opens in a new tab)
- The Pricer — Acupuncture cost (opens in a new tab)
- The Pricer — Massage Envy cost (opens in a new tab)
This page is for education only and is not medical advice. Costs are typical U.S. ranges and estimates; yours will depend on your provider, location and insurance. Talk with your doctor before starting, stopping or combining any treatment. In an emergency, call 911. See our disclaimer.
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