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Kidney Disease & Kidney Stones
About 1 in 7 U.S. adults has chronic kidney disease — and most don’t know it, because early kidney disease has no symptoms. Kidney stones are common too. This guide explains the tests, the stages, what slows kidney damage, how stones are treated and prevented, and which “natural” remedies can harm your kidneys.
Get urgent care right away — or go to an emergency room — for severe pain in your back or side (often on one side, sometimes spreading to the groin), especially with fever, chills, nausea or vomiting, or if you can’t pass urine or can pass only a little. These can be signs of a kidney stone blocking the flow of urine, or of a kidney infection (NIDDK (opens in a new tab), MedlinePlus (opens in a new tab), NHS (opens in a new tab)). A kidney infection can lead to sepsis, which can be life-threatening (NIDDK (opens in a new tab), CDC (opens in a new tab)).
Call 911 if you are confused, very drowsy or have trouble speaking (NHS (opens in a new tab)), or if you are passing little or no urine along with swelling of the feet or legs, shortness of breath or confusion. These can be signs of sudden kidney injury or sepsis (NHS (opens in a new tab), NIDDK (opens in a new tab)).
See a doctor soon about blood in your urine — pink, red or brown urine — even if there is only a little, or you aren’t sure it’s blood (NHS (opens in a new tab), NIDDK (opens in a new tab)).
Your kidneys filter your blood, remove wastes and extra water as urine, keep the body’s chemicals balanced, help control blood pressure and make hormones (MedlinePlus (opens in a new tab)). This guide covers chronic kidney disease and kidney stones, with short notes on kidney infection, sudden (acute) kidney injury and polycystic kidney disease. For kidney failure, dialysis or a transplant, see our Dialysis & Kidney Failure guide.
Chronic kidney disease (CKD)
In CKD, the kidneys are damaged and can’t filter blood as they should, so wastes and extra fluid build up. It usually develops slowly. Advanced, long-lasting CKD typically can’t be reversed and can lead to kidney failure — but the sooner you know, the sooner you can protect your kidneys (NIDDK (opens in a new tab)). Not everyone with CKD reaches kidney failure, and treatment has been shown to slow it (CDC (opens in a new tab)).
How common is it?
CDC’s estimates, updated in March 2026, found that 14 percent of U.S. adults — about 37 million people — have CKD, and 87 percent of adults with CKD didn’t know it. CKD was found in 38 percent of adults with diabetes and 21 percent of adults with high blood pressure. It was most common at age 65 and older (34 percent) and more common in non-Hispanic Black adults (22 percent) than in non-Hispanic White adults (13 percent). CDC notes the estimates come from a single round of tests and may overstate the numbers (CDC (opens in a new tab)).
Causes and symptoms
The most common causes are diabetes, which damages the kidneys’ filters, and high blood pressure, which damages their blood vessels. Others include lupus and other immune diseases, glomerular diseases, polycystic kidney disease, medicines that are toxic to the kidneys, and acute kidney injury (NIDDK (opens in a new tab)). Heart failure, a family history of CKD, and overweight or obesity also raise the risk (CDC (opens in a new tab)). See our Diabetes and Blood Pressure guides.
Early CKD usually has no symptoms. Later, people may notice swelling in the legs, feet or ankles, poor appetite or nausea, tiredness, trouble concentrating, foamy urine, itching, muscle cramps, or shortness of breath (NIDDK (opens in a new tab)).
The two tests — and your stage
Testing is the only way to know how well your kidneys work, and the same two tests track CKD over time (NIDDK (opens in a new tab)):
- eGFR (estimated glomerular filtration rate), a blood test that uses your creatinine level to estimate how well your kidneys filter (MedlinePlus (opens in a new tab)). An eGFR under 60 may mean kidney disease; under 15 may mean the kidneys are failing (CDC (opens in a new tab)).
- UACR (urine albumin-to-creatinine ratio), a urine test for albumin, a protein that leaks into urine when kidneys are damaged. A result of 30 mg/g or less is normal; above 30 may be a sign of kidney disease, and the test may be repeated to confirm it (NIDDK (opens in a new tab)).
By eGFR, stage 1 is a normal eGFR (above 90) with other signs of kidney damage; stage 2 is 60–89 with signs of damage; 3a is 45–59; 3b is 30–44; 4 is 15–29; and 5 is below 15, when the kidneys have lost almost all their function. Urine albumin is graded A1 to A3; for both, a higher stage means more severe disease (NHS (opens in a new tab)). Ask your clinician what your own numbers mean (MedlinePlus (opens in a new tab)). People with diabetes should be tested every year; people with high blood pressure, heart disease or a family history of kidney failure should ask how often (NIDDK (opens in a new tab)).
CKD also raises the risk of heart disease and stroke (CDC (opens in a new tab)) — see our Heart guide — and of anemia, bone problems, high potassium and sudden kidney injury (NIDDK (opens in a new tab)).
Kidney stones
Kidney stones are hard, pebble-like pieces that form when urine has high levels of certain minerals. A small stone may pass on its own; a larger one can get stuck, block urine and cause severe pain or bleeding. About 11 percent of men and 6 percent of women in the U.S. have a stone at least once. The four main types are calcium stones (the most common), uric acid stones, struvite stones that may follow a urinary infection, and cystine stones from an inherited disorder. Not drinking enough, a past stone, a family history, obesity and gout all raise the risk (NIDDK (opens in a new tab)).
Stone pain usually starts in the side or lower back, may spread to the groin, and can come and go in waves. Other signs include blood in the urine, pain or urgency when urinating, cloudy urine, nausea, vomiting, fever and chills (NIDDK (opens in a new tab), NHS (opens in a new tab)). Urine and blood tests and a scan confirm a stone (MedlinePlus (opens in a new tab)).
Other kidney problems, in brief
Kidney infection (pyelonephritis) is a urinary tract infection that usually starts in the bladder and spreads up to the kidneys. It causes fever and chills, back, side or groin pain, painful urination and sometimes vomiting; seek care right away (NIDDK (opens in a new tab)). It is treated with antibiotics, sometimes through an IV in the hospital (NIDDK (opens in a new tab)). It is more likely in women, during pregnancy, and with a blockage such as a stone (NIDDK (opens in a new tab)). See our Cystitis guide.
Acute kidney injury (AKI) is a sudden drop in kidney function. Causes include infection, dehydration, blockages such as stones, some medicines including NSAIDs, and contrast dye used in some scans. Many people recover fully within weeks, but some are left with chronic kidney disease (NHS (opens in a new tab)).
Polycystic kidney disease (PKD) is an inherited disorder in which many fluid-filled cysts grow in the kidneys. It is a form of CKD that may lead to kidney failure, and it affects about 500,000 people in the U.S. (NIDDK (opens in a new tab)). A child has a 1 in 2 chance of inheriting the main adult form if one parent has it (NHS (opens in a new tab)).
Side by side
Six approaches compared
For every condition we look at the same six approaches: what each involves, what it typically costs, and what a patient can realistically expect.
| Approach | What it involves | Estimated cost | What to expect |
|---|---|---|---|
| Conventional medicine (AMA) | CKD: blood pressure and blood sugar control, ACE inhibitors or ARBs, SGLT2 inhibitors, finerenone for some people with type 2 diabetes, avoiding NSAIDs, medicine reviews and a dietitian. Stones: pain relief, sometimes an alpha blocker, lithotripsy or ureteroscopy, then prevention by stone type. | Medicare covers dietitian visits (medical nutrition therapy) at no cost for kidney disease with a referral, and up to 6 kidney disease education sessions at stage 4. Stone procedures: cost estimate being researched. | Treatment can’t cure CKD but can slow it and lower heart risks. Most stones pass on their own; larger ones are broken up or removed. |
| Chiropractic | No role. We found no evidence that chiropractic care treats kidney disease, kidney stones or kidney infection. | Not recommended for kidney problems, so no cost estimate is given. | Back or side pain from a stone or infection needs medical care first. |
| Acupuncture | Studied as an add-on for the sudden pain of a kidney stone (renal colic). We found little research on acupuncture for chronic kidney disease. | About $90–$185 per follow-up visit and $125–$230 for a first private visit (cash prices). Medicare covers acupuncture only for chronic low back pain. | Small, mostly lower-quality trials suggest faster relief of renal colic. It doesn’t remove stones or treat CKD. |
| Herbal medicine | Not a treatment. Many herbs and supplements are dangerous with CKD (aristolochic acid, high-potassium products, star fruit). Chanca piedra for stones has limited evidence; cranberry doesn’t treat kidney disease. | Not applicable — check every product with your care team first. | Possible harm, including kidney damage, dangerous potassium levels and interactions with your medicines. |
| Massage therapy | No role in treating kidney disease or stones. Gentle massage for comfort only, never on a dialysis access arm. | Not a kidney treatment, so no cost estimate is given. | Comfort at most. New swelling needs a medical check, not massage. |
| MBHA Wellness Coach | Fluids to prevent stones, less salt, home blood pressure checks, diabetes care, safer pain relief, screening if you’re at risk, protein with a dietitian, quitting smoking. | MBHA coaching: being researched. | Supports — never replaces — your medical team. Daily habits help slow CKD and prevent stones. |
Approach 1 of 6
Conventional medicine (AMA)
A primary care clinician usually leads, with a nephrologist (kidney specialist) if CKD is complicated, advanced or worsening quickly; a dietitian and pharmacist are key team members (NIDDK (opens in a new tab)). A urologist treats stones (NIDDK (opens in a new tab)). We name medicines but never doses.
Slowing chronic kidney disease
- Blood pressure control is the most important step, and meeting your blood sugar goals matters if you have diabetes (NIDDK (opens in a new tab)). Aim for the target your clinician sets (CDC (opens in a new tab)).
- ACE inhibitors and ARBs (names ending in –pril or –sartan) may slow kidney disease and delay kidney failure, even without high blood pressure (NIDDK (opens in a new tab)).
- SGLT2 inhibitors. Dapagliflozin’s FDA-approved label includes lowering the risk of kidney function decline, kidney failure, cardiovascular death and heart failure hospitalization in adults with CKD at risk of getting worse; it is not recommended for CKD caused by polycystic kidney disease (FDA label (opens in a new tab)). Empagliflozin is also used to reduce the risk of worsening kidney disease in certain adults (MedlinePlus (opens in a new tab), MedlinePlus (opens in a new tab)). They don’t suit everyone (NHS (opens in a new tab)).
- Finerenone was FDA-approved in 2021 to lower kidney and heart risks in adults with CKD linked to type 2 diabetes; side effects include high potassium and low blood pressure (FDA (opens in a new tab)).
- Statins or other cholesterol medicines help protect the heart (NHS (opens in a new tab)).
- Avoid NSAIDs such as ibuprofen and naproxen unless a clinician advises them; they can damage the kidneys and cause acute kidney injury (NIDDK (opens in a new tab), NHS (opens in a new tab)).
- Medicine reviews. As kidney function falls, medicines can build up, so your clinician may lower a dose, give it less often or switch it. Tell your team about every medicine, vitamin and supplement (NIDDK (opens in a new tab)). Contrast dye used in some scans can also injure the kidneys (NHS (opens in a new tab)), so mention your CKD before a scan.
- A renal dietitian: needs for sodium, potassium, phosphorus, protein and fluids change as CKD advances, and there is no single plan for everyone (NIDDK (opens in a new tab)).
- A yearly flu shot, because people with CKD have a higher risk of severe flu (CDC (opens in a new tab)).
If kidney function keeps falling, learn about your options early in our Dialysis & Kidney Failure guide.
Treating kidney stones
- Small stones: fluids, pain medicine and anti-sickness medicine; you may be asked to catch the stone so a lab can test it (NIDDK (opens in a new tab), NHS (opens in a new tab)).
- Alpha blockers, such as tamsulosin, are sometimes used for kidney stones (MedlinePlus (opens in a new tab)). A 2018 Cochrane review of 67 studies found they likely help more stones clear but probably slightly raise the risk of major side effects, and may help less for stones 5 mm or smaller (Cochrane review, 2018 (opens in a new tab)).
- Procedures for larger or blocking stones: shock wave lithotripsy breaks the stone from outside the body; ureteroscopy passes a thin scope through the urethra to remove or break it, usually with a same-day discharge; and percutaneous nephrolithotomy works through a small cut in the back (NIDDK (opens in a new tab)). A stone that blocks urine and causes infection may need a procedure as well as antibiotics (NIDDK (opens in a new tab)).
Preventing the next stone
Prevention depends on your stone type, so ask what yours was; a 24-hour urine test may help (NIDDK (opens in a new tab)).
- Fluids, mainly water, matter most for most types; citrus drinks may also help because their citrate stops crystals becoming stones (NIDDK (opens in a new tab)).
- Calcium stones: cut sodium, limit animal protein and get enough calcium from food; for calcium oxalate stones, you may be told to limit high-oxalate foods such as spinach, rhubarb, nuts and wheat bran (NIDDK (opens in a new tab)).
- Uric acid stones: limit animal protein and lose weight if needed (NIDDK (opens in a new tab)).
- Medicines by type: potassium citrate, diuretics, allopurinol (uric acid stones) or antibiotics (struvite stones) (NIDDK (opens in a new tab)).
Polycystic kidney disease
Treatment targets blood pressure (often ACE inhibitors or ARBs), pain, stones and infections, and NSAIDs are usually avoided. Tolvaptan can slow cyst growth in some adults whose disease is worsening quickly; liver damage has been reported, so people taking it are monitored closely (NHS (opens in a new tab)).
What it costs
- Dietitian: Medicare Part B covers medical nutrition therapy for kidney disease (or a transplant in the last 36 months) with a doctor’s referral; you pay nothing if you qualify (Medicare.gov (opens in a new tab)).
- Kidney disease education: with stage 4 CKD and a referral, Part B covers up to 6 sessions; you pay 20 percent of the Medicare-approved amount after the deductible (Medicare.gov (opens in a new tab)).
- Tests, medicines and stone procedures: cost estimate being researched.
Approach 2 of 6
Chiropractic
Chiropractic care has no role in treating kidney disease, stones or infection. We found no studies showing it changes kidney function or helps stones pass.
- Kidney pain can feel like back pain. Stone pain often starts in the lower back or side (NHS (opens in a new tab)), and a kidney infection can cause back or side pain with fever (NIDDK (opens in a new tab)). Sudden, severe one-sided pain — especially with fever, vomiting, blood in the urine or trouble urinating — needs medical care first.
- PKD: trauma to the back and sides may make kidney cysts burst (NIDDK (opens in a new tab)); tell any practitioner who works on your back.
- Safety: serious side effects of spinal manipulation are very rare but may be more likely in people whose health problems raise their risk of injury (NCCIH (opens in a new tab)). Don’t accept supplements without your kidney team’s okay.
Approach 3 of 6
Acupuncture
Acupuncture doesn’t remove stones or treat CKD. Its kidney research is mostly about the sudden, severe pain of a stone (renal colic).
- A 2022 review of 15 small trials (1,210 adults) found acupuncture seemed about as effective as pain medicines, with faster onset, but the evidence was generally low quality and the authors advised caution (systematic review, 2022 (opens in a new tab)). A second 2022 review of 13 trials found faster relief and fewer side effects than standard treatment, while noting the studies were few and limited (meta-analysis, 2022 (opens in a new tab)).
- In a Chinese emergency-department trial, 80 people got a standard pain injection plus real or sham acupuncture. More in the acupuncture group had their pain halved within 10 minutes, but the need for extra pain medicine was the same (randomized trial, 2022 (opens in a new tab)). A second trial of 84 people also reported faster relief than sham (randomized trial, 2025 (opens in a new tab)). Both were small, single-center trials; acupuncture is an add-on, not a substitute for emergency assessment.
- We found little research on acupuncture for CKD itself.
Safety: done improperly, acupuncture can cause infections, punctured organs and nerve injury; needles must be sterile and single-use (NCCIH (opens in a new tab)). An arm with, or being saved for, a dialysis access needs protecting (NIDDK (opens in a new tab)), so we suggest no needles there.
Cost: about $90 to $185 per follow-up and $125 to $230 for a first private visit, or $50 to $90 at community clinics (The Pricer (opens in a new tab)). Medicare covers acupuncture only for chronic low back pain (Medicare.gov (opens in a new tab)).
Approach 4 of 6
Herbal medicine
Herbal medicine doesn’t treat kidney disease — and with CKD, many herbs and supplements are dangerous.
If you have kidney disease, check every herb, supplement and over-the-counter product with your pharmacist or clinician first (NIDDK (opens in a new tab), CDC (opens in a new tab)).
- Aristolochic acid, from Aristolochia (birthwort) and some wild ginger plants, is in some products sold as supplements or “traditional medicines”. Urinary tract cancers have been reported in people whose kidneys were damaged by them; don’t use them (National Cancer Institute (opens in a new tab)). Other plant compounds, contamination with heavy metals and adulteration can also harm the kidneys (review, 2018 (opens in a new tab)).
- Hidden potassium. Too much potassium can cause heart and muscle problems in CKD. Salt substitutes can be high in it (NIDDK (opens in a new tab)), and noni contains a substantial amount (NCCIH (opens in a new tab)). Case reports show salt substitutes and supplements can cause dangerously high potassium (review of case reports, 2019 (opens in a new tab)), a cause that may be overlooked in CKD (case report, 2016 (opens in a new tab)).
- Licorice root has been linked to severe effects, including irregular heartbeat, in people with high blood pressure or heart or kidney conditions (NCCIH (opens in a new tab)).
- Interactions and hidden ingredients: supplements may interact with medicines, and some contain ingredients not on the label (NCCIH (opens in a new tab)).
- Star fruit can be poisonous with kidney disease: a review of 123 published cases found 22 percent died (systematic review, 2017 (opens in a new tab)), and effects range from hiccups to prolonged seizures (review, 2021 (opens in a new tab)). Avoid it.
Cranberry and chanca piedra
Cranberry is promoted for urinary tract infections, but there is little research for other conditions and it isn’t a treatment for an existing infection (NCCIH (opens in a new tab)). Experts don’t think diet prevents or treats kidney infections (NIDDK (opens in a new tab)), and cranberry is not a treatment for CKD or stones.
Chanca piedra (Phyllanthus niruri) is the most common ingredient in herbal stone products. A 2020 review found only two controlled studies, suggesting modest reductions in stone size and number, and called the evidence limited (meta-analysis, 2020 (opens in a new tab)). It is not a substitute for medical care. We don’t list doses.
Approach 5 of 6
Massage therapy
Massage has no role in treating kidney disease, stones or infection. Gentle massage may help some people relax, but stone or infection pain is not a muscle problem.
- Swelling is a warning sign, not a massage target. Contact your clinician about swelling in your face, arms, legs or belly (NIDDK (opens in a new tab)).
- Protect any dialysis access. Your access is your “lifeline”, and an arm being saved for one needs protecting too (NIDDK (opens in a new tab)); we suggest no massage or pressure on that arm.
- PKD: trauma to the back and sides may make cysts burst (NIDDK (opens in a new tab)), so we suggest gentle pressure only and no deep work there.
- Serious harm from massage is rare, but blood clots, nerve injury and fractures have been reported, some after vigorous deep-tissue massage (NCCIH (opens in a new tab)).
Approach 6 of 6
MBHA Wellness Coach
Most of what slows CKD and prevents stones happens day to day. An MBHA Wellness Coach can help you build habits — alongside, never instead of, your medical team.
- Fluids, the right amount for you. For stones, drinking enough, mainly water, is the most important step; many clinicians suggest six to eight 8-ounce glasses a day (NIDDK (opens in a new tab)), and dark urine means drink more (NHS (opens in a new tab)). But people with CKD may need to limit fluids (NIDDK (opens in a new tab)), so ask for your own target.
- Less salt. Sodium raises blood pressure and fluid build-up and the chance of stones; most comes from packaged and restaurant food. Cook from scratch, read labels (5 percent Daily Value or less is low) and season with herbs and lemon (NIDDK (opens in a new tab), NIDDK (opens in a new tab)).
- Blood pressure at home. Ask your team about measuring it yourself (CDC (opens in a new tab)) and bring a log to visits.
- Diabetes. Meet your blood sugar targets as often as you can and have your A1C checked at least twice a year (CDC (opens in a new tab)).
- Screening. With diabetes, high blood pressure, heart disease, obesity or a family history of CKD, get tested regularly — yearly with diabetes (CDC (opens in a new tab)).
- Safer pain relief. Check labels for NSAIDs and ask your pharmacist what’s safe. Vomiting, diarrhea or not drinking enough lower blood flow to the kidneys, and NSAIDs taken while dehydrated can injure them, so ask ahead which medicines to pause when sick (NIDDK (opens in a new tab)).
- Protein with a dietitian. Some people with CKD need moderate protein, but too little causes malnutrition (NIDDK (opens in a new tab)); limiting animal protein can help prevent some stones (NIDDK (opens in a new tab)).
- Quit smoking. Smoking can worsen kidney disease and interfere with blood pressure medicine (CDC (opens in a new tab)); free coaching is at 1-800-QUIT-NOW (CDC (opens in a new tab)).
- Move, sleep, cope. Be active most days, aim for a healthy weight and 7 to 8 hours of sleep, and ask for help if you feel down — depression is common with long-term illness (NIDDK (opens in a new tab)). Activity helps at every stage of CKD (CDC (opens in a new tab)).
Another approach
Questions to ask at your next visit
- What are my eGFR and urine albumin, and have they changed? What stage am I in? (NIDDK (opens in a new tab), NHS (opens in a new tab))
- Should I take an ACE inhibitor, ARB or other kidney-protecting medicine? Do any doses need to change? (NIDDK (opens in a new tab), NIDDK (opens in a new tab))
- Which pain relievers are safe for me, and what should I do with my medicines when I’m sick? (NIDDK (opens in a new tab))
- After a stone: what type was it, and do I need a 24-hour urine test? (NIDDK (opens in a new tab))
Member stories
Living with Kidney Disease & Kidney Stones? Share your experience
Real experiences help others choose. Tell us what you tried — conventional medicine, chiropractic, acupuncture, herbs, massage or coaching — what it cost and what changed.
Sources
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) — What is chronic kidney disease? (opens in a new tab)
- NIDDK — Causes of chronic kidney disease (opens in a new tab)
- NIDDK — Chronic kidney disease tests and diagnosis (opens in a new tab)
- NIDDK — Managing chronic kidney disease (opens in a new tab)
- NIDDK — Healthy eating for adults with chronic kidney disease (opens in a new tab)
- NIDDK — Preventing chronic kidney disease (opens in a new tab)
- NIDDK — Keeping kidneys safe: smart choices about medicines (opens in a new tab)
- NIDDK — Kidney stones: definition and facts (opens in a new tab)
- NIDDK — Kidney stones: symptoms and causes (opens in a new tab)
- NIDDK — Treatment for kidney stones (opens in a new tab)
- NIDDK — Eating, diet and nutrition for kidney stones (opens in a new tab)
- NIDDK — Kidney infection (pyelonephritis): definition and facts (opens in a new tab)
- NIDDK — Kidney infection: symptoms and causes (opens in a new tab)
- NIDDK — Kidney infection: treatment (opens in a new tab)
- NIDDK — Kidney infection: eating, diet and nutrition (opens in a new tab)
- NIDDK — What is polycystic kidney disease? (opens in a new tab)
- NIDDK — Hemodialysis (opens in a new tab)
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- NCCIH — Acupuncture: effectiveness and safety (opens in a new tab)
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This page is for education only and is not medical advice. Costs are typical U.S. ranges and estimates; yours will depend on your provider, location and insurance. Talk with your doctor before starting, stopping or combining any treatment. In an emergency, call 911. See our disclaimer.
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