Home / Health Conditions / Prostate Health (Enlarged Prostate, Prostatitis & Cancer Screening)
Prostate Health (Enlarged Prostate, Prostatitis & Cancer Screening)
The prostate can cause three common kinds of trouble: enlargement (BPH), inflammation (prostatitis) and cancer. Their symptoms overlap, so urinary changes are worth checking, and being unable to urinate is an emergency. PSA screening is a personal choice to talk through with a clinician.
Get medical care right away if you:
- Cannot urinate at all, or have swelling or severe pain in your lower belly. Sudden inability to urinate (acute urinary retention) can be life threatening (NIDDK (opens in a new tab), MedlinePlus (opens in a new tab)). It sometimes happens after certain cold or allergy medicines or alcohol (MedlinePlus (opens in a new tab)).
- Have fever and chills with painful, frequent, urgent urination (NIDDK (opens in a new tab), NIDDK prostatitis page (opens in a new tab)). Sudden, severe prostatitis needs immediate care (NIDDK prostatitis page (opens in a new tab)). The NHS in the UK adds that sudden confusion, slurred speech, blue, grey or blotchy skin, or severe trouble breathing may mean sepsis, a dangerous infection (NHS (opens in a new tab)).
- See blood in your urine (NIDDK (opens in a new tab), MedlinePlus (opens in a new tab)). Common causes include an enlarged prostate, prostate cancer, urinary stones and infection (NIDDK hematuria page (opens in a new tab)). Blood in your semen is also worth getting checked; benign prostate conditions and locally advanced cancer can both cause it (NCI (opens in a new tab)).
- Have great discomfort or pain in your lower belly or urinary tract (NIDDK (opens in a new tab)).
- Have pain in your back, hips or pelvis that doesn’t go away, especially together with urinary changes. NCI lists this among the symptoms of advanced prostate cancer (NCI (opens in a new tab), NCI prostate changes page (opens in a new tab)).
MBHA suggests going to an emergency department for these signs rather than waiting for an appointment. Never delay urgent care to try a chiropractic, acupuncture or massage visit, an herb or a supplement first.
What the prostate does
The prostate is a gland in the male reproductive system, just below the bladder and in front of the rectum. It surrounds the urethra, the tube that carries urine out of the body, and it helps make semen (NCI (opens in a new tab)). Because it wraps around the urethra, any change in the prostate can show up as a change in how you urinate. The prostate keeps growing with age: it is about the size of a walnut in a man’s 20s and by age 60 is often the size of a lemon (NCI (opens in a new tab)).
Three common prostate conditions
- Enlarged prostate (benign prostatic hyperplasia, BPH). The gland grows larger than normal, but not because of cancer (NIDDK (opens in a new tab)). Experts estimate it affects 5% to 6% of men ages 40 to 64 and 29% to 33% of men 65 and older, and it is the most common prostate problem in men over 50 (NIDDK (opens in a new tab)).
- Prostatitis. Inflammation of the prostate, sometimes from infection and sometimes with no clear cause. NIDDK calls it the most common urinary tract problem in men younger than 50 (NIDDK prostatitis page (opens in a new tab)).
- Prostate cancer. NCI says about one man in eight in the United States will be diagnosed, most men diagnosed do not die from it, and it occurs more often in Black men (NCI (opens in a new tab)). Prostate cancer usually grows very slowly (NCI (opens in a new tab)), and CDC says most prostate cancers grow slowly and don’t cause health problems (CDC (opens in a new tab)).
Neither BPH nor prostatitis raises the risk of prostate cancer (NCI (opens in a new tab)), but the symptoms can look alike. That is why NIDDK and MedlinePlus ask you to discuss any urinary symptoms with a health care professional (NIDDK (opens in a new tab), MedlinePlus (opens in a new tab)).
Symptoms that can come from the prostate
Common prostate-related symptoms include going to the bathroom often, a sudden strong urge to urinate, waking at night to urinate, trouble starting a stream, a weak or stop-and-start stream, and feeling that the bladder hasn’t emptied (NIDDK (opens in a new tab), MedlinePlus (opens in a new tab)). Prostatitis can also cause pain in the genital area, lower belly or lower back, and pain with ejaculation (NIDDK prostatitis page (opens in a new tab)). Early prostate cancer usually causes no symptoms (NCI (opens in a new tab)). Prostate size doesn’t predict symptoms (NIDDK (opens in a new tab)). See also our bladder problems guide and cancer guide. A Sexual Performance guide is planned for erection and ejaculation concerns.
Who is more likely to have prostate problems
You are more likely to develop BPH if you are 40 or older, have a family history of BPH, have heart and blood vessel disease, type 2 diabetes, obesity, chronic kidney disease or erectile dysfunction, or are not physically active (NIDDK (opens in a new tab)). See our diabetes, heart and kidney guides. Risk factors for prostate cancer include being 50 or older, a father, brother or son with prostate cancer, inherited gene changes such as BRCA1, BRCA2 or Lynch syndrome, African American race and a history of smoking (NCI (opens in a new tab)).
When to see a doctor: any new urinary change, pain in the pelvis or genitals, or blood in the urine or semen deserves a visit (NIDDK (opens in a new tab)). The NHS says not to be embarrassed, because a doctor will be used to talking about these symptoms (NHS (opens in a new tab)). Bring a list of every medicine you take, since some can worsen symptoms (see below), and see our medication safety guide.
Side by side
Six approaches compared
For every condition we look at the same six approaches: what each involves, what it typically costs, and what a patient can realistically expect.
| Approach | What it involves | Estimated cost | What to expect |
|---|---|---|---|
| Conventional medicine (AMA) | Evaluation by a primary care clinician or urologist: history, exam, urine and sometimes PSA blood tests. BPH: lifestyle changes, medicine classes (alpha-blockers, 5-alpha reductase inhibitors, PDE-5 inhibitors), minimally invasive procedures or surgery. Bacterial prostatitis: antibiotics. Cancer: active surveillance, surgery, radiation, hormone therapy and others. | Medicare Part B covers a PSA blood test once every 12 months for men over 50 at no cost to you; a digital rectal exam is 20% of the Medicare-approved amount after the deductible. Other costs: being researched. | Many men need only monitoring and habit changes. 5-ARI medicines can take months to help and can affect sexual function. Whether to have PSA screening is a personal decision made with your clinician. |
| Chiropractic | No role in treating BPH, prostatitis or prostate cancer; we found little research. Its main safety job here is to notice red flags and refer. | About $55 to $100 per follow-up visit paying cash, per The Pricer. Medicare covers only spinal adjustments for a subluxation. | Back, hip or pelvic pain that keeps getting worse, especially in an older man or with urinary changes, can be prostate cancer that has spread; case reports describe men who first sought chiropractic care. |
| Acupuncture | Needle treatment for chronic prostatitis and chronic pelvic pain syndrome; little research for BPH. | About $90 to $185 per follow-up visit paying cash, per The Pricer. Medicare covers acupuncture only for chronic low back pain. | For chronic pelvic pain, a Cochrane review found acupuncture reduced symptoms compared with sham needling, and a larger sham-controlled trial agreed. Side effects were mild. |
| Herbal medicine | Saw palmetto and other plant products are widely sold for prostate health. | Cost estimate being researched. | A 2023 Cochrane review found saw palmetto alone gives little or no benefit for BPH symptoms. Some supplements may be harmful for men with prostate cancer. Tell your clinician about everything you take. |
| Massage therapy | General massage is not a prostate treatment. Specialized pelvic-floor myofascial physical therapy has been studied for chronic pelvic pain. | One national chain: about $70 to $90 a month on a 12-month membership, per The Pricer. Medicare Part B covers medically necessary outpatient physical therapy (20% after the deductible). | A small feasibility trial favored myofascial physical therapy over general massage for chronic pelvic pain syndromes. Evidence for prostate massage is uncertain. |
| MBHA Wellness Coach | Everyday habits that ease urinary symptoms: fluids and timing, alcohol and caffeine, activity, weight, constipation, stress and a medicine review, plus help preparing for doctor visits and the PSA conversation. | Cost estimate being researched. | Supports — never replaces — medical evaluation. Small changes can reduce nighttime and out-of-the-house bathroom trips. |
Approach 1 of 6
Conventional medicine (AMA)
What care looks like depends on the condition; details are in the sections below. NIDDK says BPH can be treated with watchful waiting, medicines or surgery, depending on how severe the symptoms are and how they affect your quality of life (NIDDK (opens in a new tab)). Bacterial prostatitis is treated with antibiotics, while the chronic pain form has no single treatment that works for every man (NIDDK prostatitis page (opens in a new tab)). Prostate cancer options range from active surveillance to surgery, radiation and hormone therapy (NCI (opens in a new tab)). Your primary care clinician may refer you to a urologist, a doctor who specializes in the urinary tract and male reproductive system (NCI (opens in a new tab)).
What it costs
Medicare Part B covers a digital rectal exam and a PSA blood test once every 12 months for men over 50. You pay nothing for the PSA blood test itself; for the rectal exam you pay 20% of the Medicare-approved amount after the Part B deductible (Medicare.gov (opens in a new tab)). We have not yet researched other costs, such as visits, procedures or medicines.
Approach 2 of 6
Chiropractic
Chiropractic care is not a treatment for an enlarged prostate, prostatitis or prostate cancer; we found little research on it for these conditions.
Why a chiropractor should know about the prostate
Prostate cancer can spread to the spine, hips and pelvis. NCI lists pain in the back, hips or pelvis that doesn’t go away as a sign of advanced disease (NCI (opens in a new tab)). One published report describes two older men with no known cancer and no prior PSA screening who sought chiropractic care for worsening, radiating low back pain; the chiropractor ordered imaging and referred them to an oncologist, who made a presumptive diagnosis of prostate cancer. The authors also reviewed seven earlier similar cases (Chu et al., 2022 (opens in a new tab)). A second report, of a 62-year-old man with worsening hip pain, found nine earlier cases in the literature (Chu et al., 2023 (opens in a new tab)). These are case reports, so they show that it can happen, not how often.
The safety take-away: back, hip or pelvic pain that is new, keeps getting worse, or comes with urinary changes needs a medical evaluation, not only an adjustment. MBHA suggests telling any chiropractor about urinary symptoms and asking whether you need to see your doctor first. NCCIH notes that serious side effects of spinal manipulation are very rare, and that practitioners should assess patients thoroughly and patients should share their health conditions (NCCIH (opens in a new tab)).
What it costs
The Pricer lists about $55 to $100 for a self-pay follow-up visit and $90 to $200 for a first appointment (The Pricer (opens in a new tab)). Medicare covers only spinal adjustments by a chiropractor to correct a subluxation, and does not cover other services or tests a chiropractor orders (Medicare.gov (opens in a new tab)).
Approach 3 of 6
Acupuncture
The best evidence for acupuncture in prostate problems is for chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS), not for BPH. We found little research on acupuncture for BPH.
What studies found
- A Cochrane review of non-drug treatments for CP/CPPS found that, in three studies with 204 men, acupuncture reduced prostatitis symptoms compared with a sham procedure over the short term (high-quality evidence), with little to no difference in side effects. It probably also reduced symptoms more than standard medical therapy (two studies, 78 men; moderate-quality evidence) (Franco et al., 2018 (opens in a new tab)).
- In a sham-controlled trial of 440 men in China, 20 sessions over 8 weeks produced more responders than sham acupuncture (about 61% versus 37 to 38%), and the benefit was still present 24 weeks after treatment. No serious adverse events were reported; the authors noted that sham acupuncture might itself have had some effect (Sun et al., 2021 (opens in a new tab)).
- A 2023 review of ten high-quality trials (798 men) found acupuncture improved pain, symptom scores and quality of life compared with sham acupuncture and with Western medicine, with mild side effects such as bruising and pain; the authors called for larger, longer trials (Pan et al., 2023 (opens in a new tab)).
NIDDK lists acupuncture among the alternative treatments for chronic prostatitis, and the NHS says it may be offered where available (NIDDK prostatitis page (opens in a new tab), NHS (opens in a new tab)). MBHA suggests that acupuncture not replace a medical evaluation of a urinary blockage, a possible infection or a possible cancer.
Safety
NCCIH says acupuncture can cause serious problems, including infections and punctured organs, when it is not delivered properly (NCCIH (opens in a new tab)). MBHA suggests choosing a licensed practitioner who uses sterile, single-use needles, and telling them about any urinary symptoms.
What it costs
The Pricer lists about $90 to $185 per follow-up visit and up to about $230 for a first private appointment, with community acupuncture around $50 to $90 (The Pricer (opens in a new tab)). Medicare covers acupuncture only for chronic low back pain (Medicare.gov (opens in a new tab)).
Approach 4 of 6
Herbal medicine
Many products are sold for “prostate health.” Federal sources say the evidence is weak for the best-known one, and that some supplements may be harmful for men with prostate cancer. NCI says that herbal or natural remedies for an enlarged prostate may not help and can possibly cause harm, and that you should check with your doctor before trying any (NCI (opens in a new tab)). Natural doesn’t always mean safe (NCCIH (opens in a new tab)); dietary supplements are not approved by the FDA before they are sold (NCCIH saw palmetto page (opens in a new tab)).
Saw palmetto
- NCCIH says that for urinary symptoms from an enlarged prostate, saw palmetto is probably not helpful. A 2023 review of 27 studies found the herb alone provides little or no benefit for BPH symptoms, including in two NIH-funded trials, and conclusions about combination products could not be reached (NCCIH (opens in a new tab)).
- The underlying Cochrane review (27 studies, 4,656 participants) concluded that saw palmetto alone provides little to no benefit for men with these symptoms, with more uncertainty about combinations with other herbs (Franco et al., 2023 (opens in a new tab)).
- A 2022 review of five studies for chronic prostatitis / pelvic pain syndrome did not find a significant benefit (NCCIH (opens in a new tab)).
- Safety: saw palmetto is well tolerated; side effects are mild and infrequent and may include digestive symptoms, dizziness and headache. It does not appear to change PSA readings. Check with your provider before using any herb if you take medicine, because some herbs and medicines interact (NCCIH (opens in a new tab)).
Other products
NCI notes that pygeum (African cherry) and beta-sitosterol have been studied for BPH (NCI (opens in a new tab)); we did not review those studies. NIDDK mentions quercetin and bee pollen for chronic prostatitis (NIDDK prostatitis page (opens in a new tab)).
Supplements and prostate cancer
NCI says results of the large Selenium and Vitamin E Cancer Prevention Trial (SELECT) suggest men with prostate cancer should not take selenium supplements, that selenium had no effect on preventing prostate cancer in that randomized trial, and that studies of vitamin E have been mixed, with some showing an increased risk of prostate cancer (NCI (opens in a new tab)). Tell your cancer team about every supplement. MBHA lists no dose for any product. See our medication safety guide.
What it costs
Cost estimate being researched.
Approach 5 of 6
Massage therapy
General relaxation massage is not a treatment for BPH, prostatitis or prostate cancer, and we found little research on it for these conditions. Psychological stress may increase the chance of chronic pelvic pain syndrome (NIDDK prostatitis page (opens in a new tab)), so some men look for relaxation approaches; the better-studied hands-on option is below.
Pelvic-floor myofascial physical therapy
For chronic prostatitis / chronic pelvic pain syndrome, NIDDK lists physical therapy, including myofascial release — pressing and stretching the muscles and soft tissues of the lower back, pelvis and upper legs — plus Kegel exercises, relaxation exercises and biofeedback (NIDDK prostatitis page (opens in a new tab)). In a small feasibility trial of 48 people with chronic pelvic pain syndromes (23 men), 57% of those given myofascial physical therapy reported a response, compared with 21% of those given global therapeutic massage; the authors said the result warrants further study (FitzGerald et al., 2013 (opens in a new tab)). Notably, general massage did worse in that trial, so look for a physical therapist trained in pelvic floor care rather than a spa massage.
Prostate massage
A Cochrane review found two studies of prostatic massage (115 men) and was uncertain whether it reduces or increases symptoms (very low-quality evidence), with no information on side effects (Franco et al., 2018 (opens in a new tab)). MBHA suggests not trying it on your own.
Safety
NCCIH says the risk of harm from massage appears low, but rare serious problems such as a blood clot, nerve injury or bone fracture have been reported, some after vigorous deep-tissue work (NCCIH (opens in a new tab)). For people with cancer, NCCIH says massage can be part of supportive care with appropriate precautions, though evidence of benefit is not strong (NCCIH (opens in a new tab)). Tell your therapist about your diagnosis and treatments.
What it costs
One national chain’s membership runs about $70 to $90 a month on a 12-month term (The Pricer (opens in a new tab)). Medicare Part B helps pay for medically necessary outpatient physical therapy certified by your provider; after the deductible you pay 20% of the Medicare-approved amount (Medicare.gov (opens in a new tab)).
Approach 6 of 6
MBHA Wellness Coach
An MBHA Wellness Coach can help you build everyday habits that ease urinary symptoms and prepare you to get the most from medical visits — alongside, never instead of, evaluation and treatment.
Habits for urinary symptoms
For mild BPH symptoms, NIDDK suggests drinking fewer liquids, particularly before going out or to bed; avoiding or limiting alcohol and caffeine; being physically active; emptying the bladder completely; using the restroom often rather than holding urine for long periods; and avoiding or monitoring medicines that can make symptoms worse (NIDDK (opens in a new tab)). The NHS adds eating enough fiber to prevent constipation, keeping to a healthy weight, relaxing rather than straining to urinate, waiting a moment and trying again to empty the bladder, and not cutting fluids too much, which can cause urinary tract infections (NHS (opens in a new tab)). MedlinePlus also lists bladder training and exercising the muscles that control urine flow (MedlinePlus (opens in a new tab)). A coach can help you keep a drink-and-bathroom diary; the NHS says a GP will usually ask you to keep a record for at least 3 days of how much you drink and how often and how much you urinate (NHS (opens in a new tab)). See our bladder problems guide.
Researchers have not found a way to prevent BPH, but being physically active may help reduce the risk (NIDDK (opens in a new tab)). For chronic pelvic pain, a Cochrane review found low-quality evidence that a physical activity program may slightly reduce symptoms (Franco et al., 2018 (opens in a new tab)).
Medicines and substances that can make things worse
NIDDK says to tell your clinician if you take cold and cough medicines such as decongestants or antihistamines, tranquilizers, antidepressants or diuretics, since these can worsen BPH symptoms (NIDDK (opens in a new tab)). Do not stop a prescribed medicine on your own.
Stress and mood
For men whose pelvic pain is affected by psychological stress, NIDDK says stress reduction may reduce recurrence of symptoms (NIDDK prostatitis page (opens in a new tab)). A coach can help with routines for sleep, relaxation and movement. See our sleep problems guide if waking at night is the main issue.
After prostate surgery
A review of 11 randomized trials (1,028 men) found that pelvic floor muscle training, with or without biofeedback, hastens the return to continence after radical prostatectomy compared with no training (MacDonald et al., 2007 (opens in a new tab)). A coach can help you keep up the exercises your care team teaches you, and prepare questions for visits (see the PSA section below).
What it costs
Cost estimate being researched.
Another approach
Enlarged prostate (BPH) in more detail
Complications. As the prostate grows it squeezes the urethra, and the bladder muscle has to work harder. Eventually the bladder may weaken and not empty completely (urinary retention). Other complications can include blood in the urine, infections, kidney disease and bladder stones (NIDDK (opens in a new tab)). Scientists aren’t sure why BPH occurs; aging and hormone changes may play a part. NCI says that untreated BPH can lead over time to a weak bladder, backflow of urine and infections, or a blocked flow that can cause kidney failure (NCI (opens in a new tab)).
How it is diagnosed. A clinician asks about your history, every medicine you take and how much you drink, and does an exam that may include a digital rectal exam. Tests can include urinalysis, a PSA blood test, bladder-function tests, cystoscopy (a look inside the urethra and bladder) or an ultrasound (NIDDK (opens in a new tab), MedlinePlus (opens in a new tab)).
Treatment. Not everyone needs it (MedlinePlus (opens in a new tab)).
- Watchful waiting (active surveillance) with yearly checkups and the lifestyle changes in the coaching section, if the prostate is only slightly enlarged and symptoms don’t affect your quality of life (NIDDK (opens in a new tab)).
- Medicines by class: alpha-blockers, which relax muscles in the bladder neck and prostate; 5-alpha reductase inhibitors (5-ARIs), which help stop prostate growth or shrink it; and phosphodiesterase-5 inhibitors, which relax muscles around the bladder, bladder neck and prostate. Combining an alpha-blocker and a 5-ARI may work better than either alone (NIDDK (opens in a new tab)). MedlinePlus notes, using finasteride as its example of a 5-ARI, that it controls BPH but will not cure it, may take at least 6 months to improve symptoms, and can cause sexual side effects (MedlinePlus (opens in a new tab)). 5-ARIs also lower the PSA level (NCI (opens in a new tab)), so tell your clinician and the laboratory that you take one before any lab test (MedlinePlus (opens in a new tab)). We list no doses.
- Minimally invasive procedures that remove tissue or widen the urethra, such as water vapor therapy or a prostatic urethral lift (NIDDK (opens in a new tab)).
- Surgery to remove part or all of the prostate if medicines don’t help, symptoms are severe or complications develop. NIDDK says it can relieve symptoms but may not cure BPH; possible complications include painful or difficult urination, temporary leakage, infection, scar tissue and sexual problems, and about 10% of people may need more surgery within 20 years (NIDDK (opens in a new tab)). A Sexual Performance guide is planned.
Another approach
Prostatitis: inflammation of the prostate
NIDDK describes four types: chronic prostatitis / chronic pelvic pain syndrome, acute bacterial prostatitis, chronic bacterial prostatitis and asymptomatic inflammatory prostatitis, which causes no symptoms and needs no treatment (NIDDK prostatitis page (opens in a new tab)). (This NIDDK page was last reviewed in 2014, so ask your clinician about newer approaches.)
- Acute bacterial prostatitis comes on suddenly and is severe: fever, chills, burning or painful urination, pain in the genital area, groin, lower belly or lower back, and sometimes the complete inability to urinate. NIDDK says men should seek immediate medical care (NIDDK prostatitis page (opens in a new tab)).
- Chronic bacterial prostatitis has similar but milder symptoms that come and go or worsen slowly over months (NCI (opens in a new tab)); it may develop after a urinary tract infection or after treatment for acute prostatitis (NIDDK prostatitis page (opens in a new tab)).
- Chronic prostatitis / chronic pelvic pain syndrome is the most common but least understood type, with pain lasting more than three months in the genital area, lower belly or lower back and urinary symptoms. Its cause is unknown (NIDDK prostatitis page (opens in a new tab), NCI (opens in a new tab)).
Treatment. Bacterial forms are treated with antibiotics, for weeks in acute cases and longer in chronic ones, and a severe case may need a short hospital stay for fluids and antibiotics by vein. The chronic pain form is harder: antibiotics don’t help nonbacterial prostatitis, though they may be tried at first to rule out infection, and no single treatment works for every man. Clinicians may try alpha-blockers, 5-ARIs, anti-inflammatory pain relievers, muscle relaxants or nerve-pain medicines, along with sitz baths (warm baths), heat, pelvic physical therapy, relaxation exercises, biofeedback and acupuncture (NIDDK prostatitis page (opens in a new tab)). The NHS also lists cognitive behavioural therapy or counselling (NHS (opens in a new tab)).
Prostatitis does not raise the risk of prostate cancer, but it can raise the PSA level (NCI (opens in a new tab)).
Another approach
The PSA screening conversation
MBHA does not tell anyone whether to be screened. This section describes what federal health agencies say so you can have an informed talk with your clinician.
What the PSA test is
Prostate-specific antigen (PSA) is a protein made by normal and cancerous prostate cells. Cancer, BPH and prostatitis can all raise PSA in the blood. The test can follow up on prostate symptoms, monitor known prostate cancer, or screen men without symptoms (NCI (opens in a new tab)). It cannot show what is causing a high level (MedlinePlus (opens in a new tab)). CDC calls it the main screening test and says age, race, some medicines, an enlarged prostate and infection can affect the level (CDC (opens in a new tab)).
What the guidance says
- USPSTF (2018): for men 55 to 69, the decision to have periodic PSA screening should be an individual one, made after discussing the potential benefits and harms with a clinician and weighing personal values and preferences. It recommends against PSA screening for men 70 and older (USPSTF (opens in a new tab)). The task force’s page notes this topic is being updated, so ask your clinician what is current.
- CDC repeats these age groups, and notes the task force does not recommend the digital rectal exam as a screening test because of a lack of evidence on benefit (CDC (opens in a new tab)).
- NCI says the PSA test is not recommended for routine screening of the general population; most organizations recommend that people considering it first discuss risks and benefits. Some organizations recommend routine testing starting at age 40 or 45 for higher-risk men, including Black men, men with inherited BRCA2 (and to a lesser extent BRCA1) variants, and men whose father or brother had prostate cancer (NCI (opens in a new tab)). USPSTF found inadequate evidence about whether the benefits differ for African American men or men with a family history (USPSTF (opens in a new tab)).
- NHS (UK): routine PSA testing is not offered unless genetic tests show a faulty BRCA2 gene, but anyone can ask a GP about it (NHS (opens in a new tab)).
Possible benefits and harms
NCI says a meta-analysis of randomized trials found PSA screening leads to a small reduction in prostate cancer deaths over 10 years (NCI (opens in a new tab)). USPSTF estimates screening men 55 to 69 may prevent about 1.3 prostate cancer deaths and about 3 cases of metastatic cancer per 1,000 men screened over about 13 years, with no reduction in deaths from all causes shown in trials (USPSTF (opens in a new tab)). Harms include:
- False alarms and biopsies. About 6% to 7% of men have a false-positive PSA test in a given round, and only about 25% of men who have a biopsy because of a high PSA are found to have cancer. Biopsy side effects can include infection, pain and bleeding (NCI (opens in a new tab)); about 1% of biopsies lead to complications needing hospitalization (USPSTF (opens in a new tab)).
- Overdiagnosis and overtreatment. Some screen-found cancers grow so slowly they would never cause problems; follow-up of large trials suggests 20% to 50% of screen-detected cases may be overdiagnosed (USPSTF (opens in a new tab)).
- Treatment side effects. Per 1,000 men screened, USPSTF estimates about 100 are diagnosed, about 80 treated, with about 50 having sexual dysfunction and 15 urinary incontinence (NCI (opens in a new tab)).
Things that change a PSA result
Infection or inflammation of the prostate and a recent biopsy can raise PSA for a month or two; vigorous exercise such as cycling and ejaculation can raise it briefly, so NCI says to avoid these for 2 days before testing, and the NHS gives a similar 48-hour list (NCI (opens in a new tab), NHS (opens in a new tab)). There is no single cutoff for a “normal” PSA; higher levels make cancer likelier (NCI (opens in a new tab)). A high result may be followed by a repeat test in 6 to 8 weeks, continued observation, other tests such as MRI, or a biopsy (NCI (opens in a new tab)).
Questions to take with you
NCI suggests asking what prostate condition you have, what treatment is recommended and what side effects men have (NCI (opens in a new tab)). MBHA also suggests asking: What is my own risk, given my family history and background? What would we do with an abnormal result? How do I feel about the chance of a biopsy, or of treatment that might not have been needed?
Cost
Medicare covers a PSA blood test once every 12 months for men over 50 at no cost for the test (Medicare.gov (opens in a new tab)).
Another approach
Prostate cancer: symptoms and treatment overview
Early prostate cancer usually causes no symptoms. The NHS explains that it often grows on the outer part of the prostate, away from the urethra, so symptoms may not appear until it has grown or spread (NHS (opens in a new tab)). When it does cause symptoms they can include changes in urination, erection problems, and blood in the urine or semen; lower back pain and unexplained weight loss may be signs of advanced cancer. These symptoms are also common with BPH, so they don’t always mean cancer (NHS (opens in a new tab)). NCI says advanced disease can cause pain in the back, hips or pelvis that doesn’t go away, and signs of anemia such as shortness of breath, tiredness or pale skin (NCI (opens in a new tab)).
Treatment. NCI lists watchful waiting or active surveillance, surgery, radiation therapy, hormone therapy, chemotherapy, targeted therapy, immunotherapy and bone-directed treatments, and says there are treatments for bone pain (NCI (opens in a new tab)). Active surveillance means closely following the cancer with exams and tests and treating it only if it begins to grow (NCI (opens in a new tab)). In the UK ProtecT trial, more than 1,600 men with screen-found, localized prostate cancer were randomized to surgery, radiation or active surveillance, and 10-year survival was 99% in all groups (USPSTF (opens in a new tab)).
Side effects to discuss. USPSTF reports that about 1 in 5 men who have the prostate removed develop long-term urinary incontinence requiring pads, and 2 in 3 have long-term erectile dysfunction; more than half who receive radiation have long-term erectile dysfunction, and up to 1 in 6 have long-term bothersome bowel symptoms (USPSTF (opens in a new tab)). See our cancer guide. A Sexual Performance guide is planned.
Member stories
Living with Prostate Health (Enlarged Prostate, Prostatitis & Cancer Screening)? Share your experience
Real experiences help others choose. Tell us what you tried — conventional medicine, chiropractic, acupuncture, herbs, massage or coaching — what it cost and what changed.
Sources
- NIDDK — Enlarged prostate (benign prostatic hyperplasia) (opens in a new tab)
- NIDDK — Prostatitis: inflammation of the prostate (last reviewed 2014) (opens in a new tab)
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- NIDDK — Hematuria (blood in the urine) (opens in a new tab)
- National Cancer Institute (NCI) — Understanding prostate changes and conditions (opens in a new tab)
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- MedlinePlus — Prostate diseases (opens in a new tab)
- MedlinePlus — Prostate-specific antigen (PSA) test (opens in a new tab)
- MedlinePlus — Finasteride (drug information) (opens in a new tab)
- NHS — Enlarged prostate (opens in a new tab)
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- NCCIH — Using dietary supplements wisely (opens in a new tab)
- NCCIH — Acupuncture: effectiveness and safety (opens in a new tab)
- NCCIH — Massage therapy: what you need to know (opens in a new tab)
- NCCIH — Spinal manipulation: what you need to know (opens in a new tab)
- Franco et al. — Non-pharmacological interventions for chronic prostatitis / chronic pelvic pain syndrome, Cochrane Database Syst Rev, 2018 (PubMed) (opens in a new tab)
- Franco et al. — Serenoa repens for lower urinary tract symptoms due to benign prostatic enlargement, Cochrane Database Syst Rev, 2023 (PubMed) (opens in a new tab)
- Sun et al. — Efficacy of acupuncture for chronic prostatitis / chronic pelvic pain syndrome: a randomized trial, Ann Intern Med, 2021 (PubMed) (opens in a new tab)
- Pan et al. — Acupuncture for chronic prostatitis or chronic pelvic pain syndrome: an updated systematic review and meta-analysis, Pain Res Manag, 2023 (PubMed) (opens in a new tab)
- FitzGerald et al. — Randomized multicenter feasibility trial of myofascial physical therapy for urological chronic pelvic pain syndromes, J Urol, 2013 (PubMed) (opens in a new tab)
- Chu et al. — Presumptive prostate cancer presenting as low back pain in the chiropractic office: two cases and literature review, Cureus, 2022 (PubMed) (opens in a new tab)
- Chu et al. — Prostate cancer presenting as hip pain at the chiropractic office: a case report and literature review, Cureus, 2023 (PubMed) (opens in a new tab)
- MacDonald et al. — Pelvic floor muscle training to improve urinary incontinence after radical prostatectomy: a systematic review, BJU Int, 2007 (PubMed) (opens in a new tab)
- Medicare.gov — Prostate cancer screenings (opens in a new tab)
- Medicare.gov — Physical therapy services (opens in a new tab)
- Medicare.gov — Chiropractic services (opens in a new tab)
- Medicare.gov — Acupuncture (opens in a new tab)
- The Pricer — Chiropractor and chiropractic treatment cost (opens in a new tab)
- The Pricer — Acupuncture cost (opens in a new tab)
- The Pricer — Massage Envy cost (one national chain) (opens in a new tab)
This page is for education only and is not medical advice. Costs are typical U.S. ranges and estimates; yours will depend on your provider, location and insurance. Talk with your doctor before starting, stopping or combining any treatment. In an emergency, call 911. See our disclaimer.
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